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Gluco- and mineralocorticoid receptors (GR and MR) act via common promoter elements but may exert different effects on gene regulation in various regions of the forebrain. In order to separately analyse the role of GR and MR in the regulation of neurotrophic factor genes and their receptors, we used adrenalectomy and subsequent hormone injections in the rat(More)
A strong neurotensin-like immunoreactivity (NT-like IR) was detected in the odontoblast cells of the rat teeth. 4 h after a partial pulpotomy performed in two maxillary molar teeth a decreased NT-like IR was observed in the odontoblast layer located at the vicinity of the lesion together with edema and nuclear pyknosis. NT-like IR became further decreased(More)
1. The mapping of glucocorticoid receptors (GR) in the rat central nervous system (CNS) has demonstrated their widespread presence in large numbers of nerve and glial cell populations also outside the classical stress regions. 2. The present paper summarizes the evidence that glucocorticoids via GR in the CNS can act as lifelong organizing signals from(More)
Microdensitometrical and stereological techniques were applied to study the effects of aging on the hippocampus of 3-, 6-, 12-, 18-, 24-, 30-, and 36-month-old male Brown Norway rats. Stereological analysis of basic fibroblast growth factor (bFGF) immunoreactive glial cells in the CA1 area showed an age-dependent decrease in the number of cells, starting at(More)
A detailed mapping of glucocorticoid receptor (GR) immunoreactivity (IR) in rat CNS was performed employing a mouse monoclonal antibody against rat liver GR. Subjective comparisons were made between the present results and the available data in the literature. A semiquantitation of GR immunostaining was found necessary and was obtained by microdensitometric(More)
Progress of wound healing is critically dependent on the balance between oxidants and antioxidants at the wound site, and transition metals such as iron can exacerbate ROS generation. In the present study, cyanobacterial exopolymers from three strains of Anabaena and Tolypothrix tenuis have been characterized for their antiradical and Fe2+-chelating(More)
A culture-independent diversity assessment of archaea, bacteria and fungi in the Thar Desert in India was made. Six locations in Ajmer, Jaisalmer, Jaipur and Jodhupur included semi-arid soils, arid soils, arid sand dunes, plus arid cryptoendolithic substrates. A real-time quantitative PCR approach revealed that bacteria dominated soils and cryptoendoliths,(More)
Inhibitory effects of a fresh leaf juice of the Withania somnifera (W.s.) on the enzymes acetylcholinesterase (AChE; EC 3.1.17) and nicotinamide adenine dinucleotide diaphorase (NADPH-d) were studied in the mice brain using histochemical and biochemical approaches. The results obtained show significant reduction in the number of and reaction intensity in(More)
The desert cyanobacterium Anabaena variabilis produces an exopolymer during the stationary growth phase in batch culture. Optimal polymer production was observed at pH 10 under phosphorus limitation. Chemical analysis showed it to be composed of 49% carbohydrate and 19% protein. Monosaccharide analysis revealed a heteropolysaccharidic nature with glucose,(More)
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