Monica A. Murray

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We have used enhancer trap lines as markers to recognize glial cells in the wing peripheral nervous system of Drosophila melanogaster. Their characterization has enabled us to define certain features of glial differentiation and organization. In order to ask whether glial cells originate within the disc or whether they migrate to the wing nerves from the(More)
Sensory neurons in the wing of Drosophila originate locally from epithelial cells and send their axons toward the base of the wing in two major bundles, the L1 and L3 nerves. We have estimated the birth times of a number of identified wing sensory neurons using an X-irradiation technique and have followed the appearance of their somata and axons by means of(More)
The sensory neurons of the wing of Drosophila arise during the first 24 hr of metamorphosis, and their axons converge to form a stereotyped set of nerves projecting proximally from the peripherally located cell bodies through the wing and towards the CNS. To better characterize the cues guiding this stereotyped axon outgrowth, we have performed a series of(More)
Growing axons can be guided by a number of different cues: adhesive substrates, diffusible factors, electrical fields and even factors intrinsic to the neurone itself have all been shown to affect axon orientation and outgrowth in vitro. However, in most intact systems it has proved difficult to test directly the role played by these putative guidance cues.(More)
A new monoclonal antibody, specific to an epitope in the carboxyl terminus of the Drosophila collagen IV molecule (basement membrane collagen) was identified. The distributions of collagen IV, laminin, and an additional extracellular molecule, the 2G2 antigen (2G2-Ag), were followed immunocytochemically during early wing development. In late third instar(More)
service is not limited to cable programming , the Cable Act preempted only laws regarding the provision of cable services, not all cable services generally. United States Court of Appeals for the Eighth Circuit held that the seller of a chemical plant site was 100 percent responsible for the environmental cleanup costs incurred by the purchaser because the(More)
whether the regulation directly advanced the government's interest. The lower court did not have the benefit of a recent Supreme Court case that provides the framework for determining whether a regulation directly advances the govern-ment's interest. The Tenth Circuit stated that on remand, the district court must determine whether the government(More)
Mitochondrial DNA (mtDNA) was isolated from liver mitochondria of rats between 2 and 24 months of age. The mtDNA was purified by cesium chloride--ethidium bromide isopycnic density gradient centrifugation. In the gradients, in addition to the two expected bands of ethidium--DNA complex, there was observed a third, more dense band (d = 1.69 g/cm3). This(More)
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