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Biology of breast cancer bone metastasis
- Mojtaba Akhtari, Junaid Mansuri, Kam A Newman, T. Guise, P. Seth
- Cancer biology & therapy
- 1 January 2008
Breast carcinoma ranks among the most prevalent malignancies in women. Breast carcinoma frequently metastasizes to bone and approximately 70% of patients with breast cancer have bone metastases,… Expand
Separating graft-versus-leukemia from graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.
Routine methods to maximize the graft-versus-leukemia (GvL) activity of allogeneic hematopoietic stem cell transplantation (HSCT) without the detrimental effects of graft-versus-host disease (GvHD)… Expand
Targeting TGFβ Signaling for Cancer Therapy
Transforming growth factor (TGF) βs are multifunctional polypeptides that regulate several cellular functions, including cell growth and differentiation, extra cellular matrix production, motility… Expand
Targeting TGF beta signaling for cancer therapy
- Sravisht Iyer, Zhen-Guo Wang, Mojtaba Akhtari, W. Zhao, P. Seth
- Biology, Medicine
- Cancer biology & therapy
- 1 March 2005
Transforming growth factor (TGF)?s are multifunctional polypeptides that regulate several cellular functions, including cell growth and differentiation, extra cellular matrix production, motility and… Expand
Mobilization of hematopoietic progenitors from normal donors using the combination of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor results in fewer…
- S. Lonial, Mojtaba Akhtari, +7 authors E. Waller
- Biology of blood and marrow transplantation…
- 1 March 2013
Granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) both mobilize CD34(+) stem cells into the blood when administered before apheresis but have… Expand
Hematologic manifestations of systemic lupus erythematosus
CD99 Is Highly Expressed in Acute Myeloid Leukemia (AML) and Presents a Viable Therapeutic Target
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by clonal proliferation and block of differentiation of myeloid precursors. Overall survival for patients with AML… Expand
A phase II study (NCI9775) of sapanisertib (MLN0128/TAK-228) in relapsed and/or refractory acute lymphoblastic leukemia (ALL): Interim analysis.
e18506Background: Sapanisertib (SAP) is an oral small molecule dual mTOR complex 1 and 2 (TORC1/2) inhibitor that showed activity in lymphoid neoplasms. It blocks a feedback loop involving mTORC2 a...
Extracorporeal Photopheresis Therapy For Chronic Graft-Versus-Host Disease: Response Is Associated With Content Of Dendritic Cells And T-Cells In Peripheral Blood At Initiation Of Treatment