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We describe a new approach to speech recognition, in which all Hidden Markov Model (HMM) states share the same Gaussian Mixture Model (GMM) structure with the same number of Gaussians in each state. The model is defined by vectors associated with each state with a dimension of, say, 50, together with a global mapping from this vector space to the space of(More)
This technical report contains the details of an acoustic modeling approach based on subspace adaptation of a shared Gaussian Mixture Model. This refers to adaptation to a particular speech state; it is not a speaker adaptation technique, although we do later introduce a speaker adaptation technique that it tied to this particular framework. Our model is a(More)
Although research has previously been done on multilingual speech recognition, it has been found to be very difficult to improve over separately trained systems. The usual approach has been to use some kind of " universal phone set " that covers multiple languages. We report experiments on a different approach to multilingual speech recognition, in which(More)
In this paper we present a novel approach for estimating feature-space maximum likelihood linear regression (fMLLR) transforms for full-covariance Gaussian models by directly maximizing the likelihood function by repeated line search in the direction of the gradient. We do this in a pre-transformed parameter space such that an approximation to the expected(More)
Preparation of a lexicon for speech recognition systems can be a significant effort in languages where the written form is not exactly phonetic. On the other hand, in languages where the written form is quite phonetic, some common words are often mispronounced. In this paper, we use a combination of lexicon learning techniques to explore whether a lexicon(More)
BACKGROUND Controversy exists regarding the association of cigarette smoking and renal dysfunction, particularly among African Americans, who are disproportionately affected by chronic kidney disease; therefore, we evaluated the relationship between cigarette smoking and rapid renal function (RRF) decline in the Jackson Heart Study. METHODS AND RESULTS(More)
In continuance of our search for new anticancer agents, we report herein the design, synthesis, and anticancer evaluation of oxadiazole analogues. Two series (4a-h and 4i-q) of new oxadiazole analogues were designed based on heterocyclic (1,3,4-oxadiazole)-linked aryl core of IMC-038525 (tubulin polymerization inhibitor), NSC 776715, and NSC 776715 and(More)
The purpose of oculomotor movements is maintenance of clear images on the retina. Beyond this oversimplification, it requires several different types of ocular movements and reflexes to focus objects of interest to the fovea-the only portion of retina capable of sharp and clear vision. The different movements and reflexes that execute this task are the(More)