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We describe a new approach to speech recognition, in which all Hidden Markov Model (HMM) states share the same Gaussian Mixture Model (GMM) structure with the same number of Gaussians in each state. The model is defined by vectors associated with each state with a dimension of, say, 50, together with a global mapping from this vector space to the space of(More)
We describe an acoustic modeling approach in which all phonetic states share a common Gaussian Mixture Model structure, and the means and mixture weights vary in a subspace of the total parameter space. We call this a Subspace Gaussian Mixture Model (SGMM). Globally shared parameters define the subspace. This style of acoustic model allows for a much more(More)
Although research has previously been done on multilingual speech recognition, it has been found to be very difficult to improve over separately trained systems. The usual approach has been to use some kind of “universal phone set” that covers multiple languages. We report experiments on a different approach to multilingual speech recognition,(More)
PURPOSE The aims were to determine if the maximum standardized uptake value (SUV(max)) of the primary tumor as determined by preoperative (18)F-fluoro-2-deoxyglucose ((18)F-FDG) positron emission tomography (PET) is an independent predictor of overall survival and to assess its prognostic value after stratification according to pathological staging. (More)
BACKGROUND Even after presumably curative resection the 5-year survival rates are only 60-80% in stage I and 40-50% in stage II NSCLC. Purpose of the present study was the identification of independent clinico-pathological predictors of their survival. METHODS A retrospective review of 519 consecutive subjects who had undergone attempted curative(More)
Molecular epidemiological studies have provided evidence that individual susceptibility to cancer is mediated by both genetic and environmental factors. Several allelic variants of polymorphic glutathione s-transferases (GSTs) show impaired enzyme activity and are suspected to increase the host's susceptibility to various cancers. To determine the(More)
Hyponatremia is the most common electrolyte disorder encountered in clinical practice. Patients who develop this condition for more than 48 hours are at risk for severe neurological sequelae if correction of the serum sodium occurs too rapidly. Certain medical disorders are known to place patients at an increased risk for rapid correction of serum sodium(More)
Genetic alterations in the genes expressing drug metabolizing enzymes can make an individual susceptible to various cancers. This study detects the polymorphisms at CYP1A1, GSTM1, and GSTT1 genes in a section of North Indian population and determines the susceptibility to oral submucous fibrosis (OSF). In this case–control study one hundred and two OSF(More)
BACKGROUND Difference in the capacity of xenobiotic metabolising enzymes might be an important factor in genetic susceptibility to cancer. METHODS A case control study involving forty one gastric cancer patients and one hundred and thirty controls was carried out to determine the frequency of GSTM1 and GSTT1 null genotypes. The frequency of GSTM1 and(More)