A systematic approach through computer assisted design to identify novel quinazolines having anxiolytic and GABAergic activity has been reported.
Assisted by PASS predictions, the antidepressant activity of 1,3,4-trisubstituted monocyclic beta-lactams in seasonal affective disorders is described.
PURPOSE The present study evaluates some azetidin-2-ones derivatives for their central nervous system (CNS) modulating activities. The compounds were chosen from a series (5a-o) which were previously synthesized and evaluated for hypolipidemic and antihyperglycemic activity based on the predictions made by the computer software "Prediction of Activity… (More)
Valsartan (VAL) and Hydrochlorothiazide (HTZ) are used in combination in treatment of Hypertension. Two simple, accurate, precise, economical and reproducible UV spectrophotometric methods have been developed for the estimation of Valsartan and Hydrochlorothiazide in Pharmaceutical formulation. Method I-Absorption ratio method (Q-analysis) using two… (More)