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  • Helena Viita, Johanna E. Markkanen, +8 authors Seppo Ylä-Herttuala
  • Biology, Medicine
  • Circulation research
  • 2008 (First Published: 1 February 2008)
  • Human 15-lipoxygenase-1 (15-LO-1) is an oxidizing enzyme capable of producing reactive lipid hydroperoxides. 15-LO-1 and its products have been suggested to be involved in many pathologicalContinue Reading
  • H. S. G. Roy, Shalini Bhardwaj, +7 authors Seppo Ylä-Herttuala
  • Biology, Medicine
  • Human gene therapy
  • 2005 (First Published: 14 November 2005)
  • Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family that binds specifically to VEGF receptor (VEGFR)-1. However, the mechanism of PlGF- andContinue Reading
  • H. S. G. Roy, Shalini Bhardwaj, +8 authors Seppo Ylä-Herttuala
  • Biology, Medicine
  • FASEB journal : official publication of the…
  • 2006 (First Published: 1 October 2006)
  • Plaque angiogenesis may be associated with the development of unstable and vulnerable plaques. Vascular endothelial growth factors (VEGFs) are potent angiogenic factors that can affect plaqueContinue Reading
  • Mohan Babu, Thota Durga Devi, +7 authors Seppo Ylä-Herttuala
  • Biology, Medicine
  • Circulation research
  • 2015 (First Published: 17 July 2015)
  • RATIONALE Hyperlipidemia and type 2 diabetes mellitus (T2DM) severely impair adaptive vascular growth responses in ischemic muscles. This is largely attributed to dysregulated gene expression,Continue Reading
  • Thota Durga Devi, Mohan Babu, +9 authors Seppo Ylä-Herttuala
  • Biology, Medicine
  • The American journal of pathology
  • 2017 (First Published: 1 December 2017)
  • Type 2 diabetes mellitus (T2DM) is a major risk factor for heart disease. Mortality rates after myocardial infarction (MI) are significantly increased in T2DM patients because of dysfunctional leftContinue Reading