Mohammed S. Hasan

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The efficacy of granulocyte-macrophage colony-stimulating factor (GM-CSF) to enhance the primary immune response to hepatitis B vaccine was studied in healthy elderly with young volunteers included as controls in this double-blind, placebo-controlled trial of GM-CSF as an immune adjuvant. Naïve T-helper cells (CD4+CD45RA+) were determined at baseline.(More)
Interleukin-15 (IL-15) has been reported to have many activities on T cell populations, including a potential role in improving antigen-specific proliferation in HIV-1 disease. We tested this response in healthy adults by studying the response of T cell populations after stimulation with medium, tetanus, cytomegalovirus (CMV) antigens in cultures from 21(More)
This paper introduces a new discrimination network structure called Gator that is a generalization of the widely known Rete and TREAT algorithms. Gator can be used as a replacement for Rete or TREAT in active database rule systems and production system interpreters. In Gator,-memory nodes that hold intermediate join results can have two or more inputs, not(More)
Sera from highly selected HIV-1-positive patients are known to have the ability to neutralize a diverse array of primary isolates of HIV-1. The human osteosarcoma cell line that expresses CD4 and chemokine receptors (GHOST cells) was adapted to study HIV-1 neutralization in 37 HIV-1-infected individuals who were selected because of slow disease progression(More)
This paper presents an active database discrimination network algorithm called Gator, and its implementation in a modiied version of the Ariel active DBMS. Gator is a generalization of the widely known Rete and TREAT algorithms. Gator pattern matching is explained, and it is shown how a discrimination network can speed up condition testing for multi-table(More)
This paper presents a new active database discrimination network algorithm called Gator, and its implementation in a modiied version of the Ariel active DBMS. Gator is a generalization of the widely known Rete and TREAT algorithms, and is designed as a target for a discrimination network optimizer. Ariel now has an optimizer that can choose an eecient Gator(More)
Granulocyte macrophage colony-stimulating factor (GM-CSF) has shown promise as an adjuvant to improve the kinetics and magnitude of the immune response after vaccination. It was hypothesized that GM-CSF given intramuscularly (IM) with hepatitis B vaccine would result in increased seroconversion rates and antibody titers. In total, 108 healthy volunteers(More)
We present a case of cerebral zygomycosis that did not respond to standard treatment with amphotericin B or amphotericin B lipid complex. The patient was eventually cured through a combination of surgery and the use of high dose liposomal amphotericin B. Since penetration of the central nervous system by amphotericin B is poor the application of high dose(More)
This paper brieey presents a new discrimination network algorithm called Gator that is a generalization of the widely known Rete and TREAT algorithms. Gator is designed as a target for a discrimination network optimizer. Several strategies for optimizing Gator networks were implemented, and then tested and compared using randomly generated simulated rule(More)
Behçet's disease (BD) is an autoinflammatory, chronic relapsing/remitting disease of unknown aetiology with both innate and acquired immune cells implicated in disease pathogenesis. Peripheral blood natural killer (NK) cells and their CD56Dim /CD56Bright subsets were surface phenotyped using CD27 and CD16 surface markers in 60 BD patients compared to 60(More)
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