Mohammed S. Ahmed

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Acute phase reaction is a systemic response which usually follows a physiological condition that takes place in the beginning of an inflammatory process. This physiological change usually lasts 1-2 days. However, the systemic acute phase response usually lasts longer. The aim of this systemic response is to restore homeostasis. These events are accompanied(More)
AIMS Myocardial CCN2/CTGF is induced in heart failure of various etiologies. However, its role in the pathophysiology of left ventricular (LV) remodeling after myocardial infarction (MI) remains unresolved. The current study explores the role of CTGF in infarct healing and LV remodeling in an animal model and in patients admitted for acute ST-elevation MI.(More)
BACKGROUND CCL21 acting through CCR7, is termed a homeostatic chemokine. Based on its role in concerting immunological responses and its proposed involvement in tissue remodeling, we hypothesized that this chemokine could play a role in myocardial remodeling during left ventricular (LV) pressure overload. METHODS AND RESULTS Our main findings were: (i)(More)
ii Dedication To my beloved mother. & To my lovely wife Hanaa, and my kids Ahmed and Malack. iii Acknowledgments I would like to express my sincere gratitude to my dissertation advisor, Dr. Yong-June Shin, for his invaluable support and guidance throughout my doctoral study in the University of South Carolina. His continual, enthusiastic efforts to expand(More)
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