Mohammed Khaleel Jameel

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Field carcinogenesis detection represents a promising means for colorectal cancer (CRC) screening, although current techniques (e.g., flexible sigmoidoscopy) lack the requisite sensitivity. The novel optical technology low-coherence enhanced backscattering (LEBS) spectroscopy, allows identification of microscale architectural consequences of the field(More)
BACKGROUND & AIMS We previously used a novel biomedical optics technology, 4-dimensional elastically scattered light fingerprinting, to show that in experimental colon carcinogenesis the predysplastic epithelial microvascular blood content is increased markedly. To assess the potential clinical translatability of this putative field effect marker, we(More)
There has been significant interest in developing depth-selective optical interrogation of biological tissue in general and of superficial (e.g., mucosal) tissue in particular. We report an in vivo polarization-gating fiber-optic probe that obtains backscattering spectroscopic measurements from a range of near-surface depths (100-200 microm). The design and(More)
PURPOSE Endoscopic examination has proven effective in both detecting and preventing colorectal cancer; however, only about a quarter of eligible patients undergo screening. Even if the compliance rate increased, limited endoscopic capacity and cost would be prohibitive. There is a need for an accurate method to target colonoscopy to those most at risk of(More)
Flexible sigmoidoscopy is a robust, clinically validated, and widely available colorectal cancer screening technique that is currently sanctioned by major guideline organizations. Given that endoscopic visualization is generally limited to the distal third of the colon and women tend to have a proclivity for proximal lesions, the flexible sigmoidoscopy(More)
A method to predict 28-day compressive strength of high strength concrete (HSC) by using MFNNs is proposed in this paper. The artificial neural networks (ANN) model is constructed trained and tested using the available data. A total of 368 different data of HSC mix-designs were collected from technical literature. The data used to predict the compressive(More)
PURPOSE We previously reported that analysis of histologically normal intestinal epithelium for spectral slope, a marker for aberrations in nanoscale tissue architecture, had outstanding accuracy in identifying field carcinogenesis in preclinical colorectal cancer models. In this study, we assessed the translatability of spectral slope analysis to human(More)
Aims: Stress can be defined according to Psychoneuroimmunology experts as 'environmental events (real or perceived) that perturb one's psychological or physiological homeostasis or balance'. (1) Acute stress triggers release of several hormones in animals. Severity of discomfort experienced by the animal is directly proportional to an increase in(More)
With the ongoing development in the computer science areas of artificial intelligence and computational intelligence, researchers are able to apply them successfully in the construction industry. Given the complexities indeep beam behaviour and the difficulties in accurate evaluation of its deflection, the current study has employed the Adaptive(More)
This paper describes an extension of the perturbation Monte Carlo method to model light transport when the phase function is arbitrarily perturbed. Current perturbation Monte Carlo methods allow perturbation of both the scattering and absorption coefficients, however, the phase function can not be varied. The more complex method we develop and test here is(More)