Mohammed A Majid

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Choroidal neovascular membrane (CNVM) formation is a well-documented sight-threatening complication of posterior segment intraocular inflammation (PSII). The aim of this article is to review the basic and clinical science literature on the pathogenesis of CNVM formation in PSII and to present results of a case series. We searched the literature using the(More)
C-terminal domain tissue inhibitor of metalloproteinases-3 (TIMP-3) mutations cause the rare hereditary blindness Sorsby's fundus dystrophy (SFD), which involves loss of retinal pigment epithelial (RPE) cells. Since wild-type TIMP-3 causes apoptosis, we investigated whether SFD TIMP-3 might kill RPE and other cells. Plasmid-mediated overexpression of(More)
Keratoconus is a disease in which the central cornea becomes thinned. This could result from corneal stromal cell apoptosis or be induced or perpetuated by the activation of matrix degrading enzymes, particularly members of the matrix metalloproteinase (MMP) family. In some circumstances, the MMP inhibitors TIMP-1 and TIMP-3 exhibit anti-apoptotic and(More)
PURPOSE To report the clinical features of eight patients presenting with emulsification of the heavier than water vitreous substitute, Densiron-68. METHODS Two patients underwent primary inferior retinal detachment (RD) surgery, two patients underwent giant retinal tear repair, three patients had repair of inferior RD complicated by proliferative(More)
PURPOSE To assess the validity and repeatability of partial coherence interferometry (IOLMaster) and A-scan ultrasound measurement of axial length (AL) in children. METHODS A prospective comparison of AL measurement made by the IOLMaster optical instrument (Carl Zeiss) and ultrasound A-scan (Alcon) was performed. A total of 20 children (11 male, nine(More)
BACKGROUND Sorsby's fundus dystrophy (SFD) and age related macular degeneration (ARMD) are retinal diseases associated with a high level of accumulation of mutant and wild type TIMP-3, respectively, in Bruch's membrane. The pathogenic role of TIMP-3 in these diseases is uncertain, but causative mutations have been identified in the TIMP-3 gene of patients(More)
The present study is designed to know whether the enzymes related to permeability and general metabolism of the cells of testis and epididymis are affected by alpha-chlorohydrin. For this purpose two enzymes, viz., acid and alkaline phosphatases are studied thoroughly by qualitative and quantitative parameters during single high dose (90 mg/kg body weight)(More)
This paper presents a technique that intends to recognize bangla characters from Bangladeshi automobile registration plates. Even though the recognition of characters from registration plates are nothing new but the conditions and circumstances surrounding the recognition process that is going to be discussed in due course of this paper is something i.e.(More)
Keratoconus is an ocular condition that causes corneal thinning, cone formation and scarring. In view of a hypothesis that activated MMP-2 may initiate or facilitate disease progression, the MMP-2/TIMP systems of stromal cells derived from normal and keratoconic corneas have been compared. To achieve this, stromal cell cultures were established from normal,(More)