Mohammed A. Aziz

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BACKGROUND Curcumin exhibits anti-diabetic activities, induces heme-oxygenase-1 (HO-1) and is an inhibitor of transcriptional co-activator p300. A novel water soluble curcumin derivative (NCD) has been developed to overcome low invivo bioavailability of curcumin. We evaluated the effect of the NCD on signaling mechanisms involved in cardiomyocyte(More)
Foam on the ocean surface significantly increases the brightness temperatures measured by microwave radiometers. Previous results have shown that the microwave emissivity of foam on a calm water surface is significantly less than one and depends upon polarization and incidence angle. Recent radiometric and video observations of large-scale breaking waves(More)
The aim of our project was to develop a method to examine the deep masticator space of the rhesus macaque ( Macaca mulatta) in order to investigate the following particulars of the mandibular nerve: (1). its manner of entry into the masticator space, (2). its branching within spaces/canals in the spheno-temporal bony complex, and (3). the location of its(More)
BACKGROUND Hyperglycemia induces activation of the c-Jun N-terminal kinase (JNK) pathway, which suppresses insulin gene expression and reduces DNA binding of pancreatic and duodenal homeobox factor (PDX)-1. This study aims to investigate the effects of a novel curcumin derivative (NCD) on JNK signaling pathway on insulin synthesis and secretion in(More)
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