Mohammad Reza Sharbafchi

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OBJECTIVE Preclinical studies and early pilot clinical investigations have suggested that N-acetylcysteine (NAC) may be useful in treatment of methamphetamine (METH) dependence. The present study evaluated whether NAC would suppress craving to the METH. METHODS In a double-blind, controlled crossover clinical trial, 32 METH-dependent volunteers were(More)
BACKGROUND Methamphetamine (METH) abuse and dependence present a major global problem. We investigated the efficacy of adding buprenorphine in reducing METH cravings during treatment with the Matrix program. METHODS This was a randomized, double-blind, controlled clinical trial of 40 men between the age of 18 and 40 years who were referred to the(More)
BACKGROUND prevention of suicide is one of priority world health. Suicide is one of the preventable causes of death. The aim of this study is evaluation of telephone follow up on suicide reattempt. MATERIALS AND METHODS This randomized controlled clinical trial is a prospective study which has been done in Noor Hospital of Isfahan-Iran, at 2010. 139(More)
BACKGROUND Methamphetamine dependence lead to the compulsive use, loss of control, and social and occupational dysfunctions. This study aimed to compare the effect of valproate in reducing the craving in methamphetamine dependents. MATERIALS AND METHODS This is a randomized, double-blind, controlled clinical trial on 40 men of 18-40 years old referred to(More)
OBJECTIVE The aim of this study was to investigate the effect of adding risperidone to the general behavioral treatment of masturbation in children 3-7 years old. METHODS A 4 week randomized clinical controlled trial was designed in year 2009. Samples have been chosen from children who have been referred to the Child and Adolescence Psychiatric Clinic of(More)
BACKGROUND Treating inflammatory bowel disease (IBD) with antidepressants might be of utility to improve patient's condition. The aim of this study was to assess the efficacy of Duloxetine on depression, anxiety, severity of symptoms, and quality of life (QOL) in IBD patients. MATERIALS AND METHODS In a randomized, double-blind, controlled clinical trial(More)
OBJECTIVE Antipsychotic medications are the frontline treatment for the most psychotic disorders. The aim of this study is to compare the onset of action of the first and second generation antipsychotics and the rate of their side-effects in the treatment of acute psychosis. METHODS In a double-blind, controlled clinical trial, 40 acute psychotic patients(More)
Cancer is one of the three main causes of mortality in most human communities whose prevalence is being increased. A significant part of health budget in all countries has been allocated to treat the cancer, which is incurable in many cases. It has led the global health attitude to cancer prevention. Many cancer-related risk factors have been identified for(More)
BACKGROUND Historically, substance misuse has been a serious problem faced by worldwide military personnel. Some research showed that military personnel have higher rates of unhealthy substance use than their age peers in the general population. These problems have serious consequences and may lead to significant military difficulties in the field of(More)
BACKGROUND Psychological profile of inflammatory bowel disease patients is not well studied in Iran. We investigated the psychological status of Iranian patients with ulcerative colitis (UC) and its relationship with disease activity and quality of life (QOL). MATERIALS AND METHODS A cross-sectional study was conducted on adult UC patients. The Lichtiger(More)