Mohammad Reza Doosti

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BACKGROUND The purpose of this study was to evaluate the prevalence of BRCA1 (MIM: 113705) founder mutations in familial breast cancer (BC) patients with high risks in Iran. BRCA1 is among the cancer susceptibility genes best known for high penetrance mutations. BRCA1 genotyping is now used to determine patient counseling, management decisions, and(More)
BACKGROUND Alkyl hydroperoxide reductase (AhpC) of Helicobacter pylori is considered as a diagnostic antigen. Therefore, this antigen can be used to detect H. pylori infection by stool immunoassays such as ELISA. The aim of this study was to simplify the AhpC protein purification procedures. METHODS For whole cell protein extraction, the bacterial cells(More)
BACKGROUND Colorectal cancer is the third most common cancer in both men and women in the world and the second leading cause of cancer-related deaths. The incidence of colorectal cancer has increased in Iran in the past three decades and is now considered as a serious problem for our society. This cancer has two types hereditary and non-hereditary, 80% of(More)
Raw agricultural wastes are affordable adsorbents for the removal of heavy metals from aqueous solutions. In this research, the use of almond green hull (as an eco-friendly and low-cost adsorbent) with no treatment having the ability to remove toxic hexavalent chromium (Cr (VI)) from aqueous solutions has been investigated. The influences of several main(More)
Antimicrobial peptides are evolutionary components of the immune system generated in response to microbial infections. Human catestatin CgA352–372 (SL-21) is an endogenous neuropeptide with multiple biological functions. The present study aimed to further evaluate the immunomodulatory role of SL-21 in innate immunity of lung cells and investigate its impact(More)
This study analyzed some physical and mechanical properties of concrete produced with magnetite (Fe2O3) aggregate supplied from Khaf county of Iran. Since in the concrete mix design of sand gradation is controlled and applied just by fineness modulus and being in the range of standard gradation. In this paper with fixing these two factors, the effect of(More)
Breast cancer (BC) is the most common malignancy in women and the leading cause of cancer death in females worldwide, accounting for 23% (1.38 million) of total new cancer cases and 14% (458,400) of the total cancer deaths in 2008. In the USA, the estimated number of new cases of BC in 2012 was 226,870, of which 39,510 resulted in death (American Cancer(More)
One of innovate techniques that was used for improvement of water treatment process is application of ultrasound waves. In this study, different applications of ultrasound technology in water treatment process such as membrane filtration, turbidity and total suspended solid reduction, algae removal, disinfection process, water softening process and other(More)
Fanconi anemia (FA) is a rare disease, but it is the most common among the inherited bone marrow failure syndromes. In the present study, one family diagnosed with Fanconi anemia was examined. There was a 22-year-old female in this family who was diagnosed with both breast cancer and with Fanconi anemia. The chromosomal breakage in karyotyping was(More)
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