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We introduce the concept of utilizing two cell libraries, one for synthesis and another for physical design. The physical library consists of only 9 functions, each with several drive and beta ratio options, for a total cell count of 186. We show that synthesis performs better with the inclusion of more complex cells (but only if they are power efficient),(More)
Fusion proteins have unique oncogenic properties and their identification can be useful either as diagnostic or therapeutic targets. Next generation sequencing data have previously shown a fusion gene formed between Rad51C and ATXN7 genes in the MCF7 breast cancer cell line. However, the existence of this fusion gene in colorectal patient tumor tissues is(More)
The widely used genetic pleiotropic analysis of multiple phenotypes are often designed for examining the relationship between common variants and a few phenotypes. They are not suited for both high dimensional phenotypes and high dimensional genotype (next-generation sequencing) data. To overcome these limitations, we develop sparse structural equation(More)
Proteins are biological polymers of amino acid residues. Proteins perform various functions within living organisms. Multiple proteins carry out these tasks by forming functional modules. Each functional module possesses community structure. For identifying functional modules, a lot of community detection or clustering algorithms were designed , but most of(More)