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The dependence of the fracture energy and the effective process zone length on the specimen size as well as the crack extension from the notch is analyzed on the basis of Bazant's approximate size effect law. The fracture energy and the effective length of the fracture process zone is defined on the basis of the extrapolation to an infinite specimen size,(More)
The paper shows that a previously proposed size effect law can be used to identify nonlinear fracture properties solely from measured maximum loads of geometrically similar ceramic fracture specimens of sufficiently different sizes. This law represents a first-order global approximation of the deviations from linear elastic fracture mechanics, independent(More)
Multi-mode fibers (MMF) are typically used in LAN applications, in links which may reach or exceed 300 meters. Widespread use of electronic dispersion compensation (EDC) for MMF is prompted by the ratification of the 10GBASE-LRM standard [1]. A number of studies have demonstrated the superiority of MLSD for this application (see [2] and references therein).(More)
Human Leukocyte Antigen G (HLA-G) gene polymorphism and expression rate have recently been suggested to have a potential role in susceptibility to Multiple Sclerosis (MS), a chronic inflammatory demyelinating and neurodegenerative disease of the central nervous system with unknown etiology. The aim of this study was to investigate the association of the(More)
In most species the length of a pregnancy exceeds that of the luteal phase of the ovarian cycle. The conceptus within the uterus, therefore, is believed to produce a substance or substances which directly or indirectly prolong the lifespan of the corpus luteum and prevent a return to ovarian cyclicity. This phenomenon is known as maternal recognition of(More)
Ovine trophoblast protein-1 (oTP-1), the major product secreted by the trophectoderm of the sheep conceptus between days 13 and 21 of pregnancy, is considered to mediate maternal recognition of pregnancy by maintaining the function of the corpus luteum. Its amino acid sequence has 40-55% identity with various mammalian interferons-alpha (IFN-alpha), and it(More)
Some studies showed that piperine (the alkaloid of piper nigrum) can change the activities of microsomal enzymes. Midazolam concentration is applied as a probe to determine the CYP3A enzyme activity. This study was done to determine piperine pretreatment role on midazolam plasma concentration. Twenty healthy volunteers (14 men and 6 women) received oral(More)
There are some evidences for suggesting that adipose derived stem cells (ADSCs) can be differentiated to the fate of neural cell type. ADSCs can be expanded rapidly in vitro and can be obtained by a less invasive method. In this study, we attempted to compare the stability of neural differentiation in human ADSCs by using two induction protocols. Isolated(More)
Nonsyndromic patent ductus arteriosus (PDA) is a common congenital heart defect (CHD) with both inherited and acquired causes, but the disease mechanisms have remained elusive. Using combined genome-wide linkage analysis and whole-exome sequencing (WES), we identified independent mutations in PRDM6, which encodes a nuclear protein that is specific to(More)