Mohammad Hedayati

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  • Sushant K. Kachhap, Nadine Rosmus, Spencer J. Collis, Madeleine S. Q. Kortenhorst, Michel D. Wissing, Mohammad Hedayati +10 others
  • 2010
BACKGROUND Histone deacetylase inhibitors (HDACis) re-express silenced tumor suppressor genes and are currently undergoing clinical trials. Although HDACis have been known to induce gene expression, an equal number of genes are downregulated upon HDAC inhibition. The mechanism behind this downregulation remains unclear. Here we provide evidence that several(More)
Human RECQL5 is a member of the RecQ helicase family which is implicated in genome maintenance. Five human members of the family have been identified; three of them, BLM, WRN and RECQL4 are associated with elevated cancer risk. RECQL1 and RECQL5 have not been linked to any human disorder yet; cells devoid of RECQL1 and RECQL5 display increased chromosomal(More)
MicroRNAs (miRNAs) have been implicated in DNA repair pathways through transcriptional responses to DNA damaging agents or through predicted miRNA regulation of DNA repair genes. We hypothesized that additional DNA damage regulating miRNAs could be identified by screening a library of 810 miRNA mimetics for the ability to alter cellular sensitivity to(More)
This article proposes a model to track contenders (jockeys) in horse races from broadcast videos based on the colour property of contenders. To overcome the effects of background noise and occlusion the proposed system merges contextual information of the horse race into a colour-based tracking framework (mean shift). There are two improvements. The first(More)
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