Mohammad Bagher Ghoshoon

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A unicellular microalga, Chlamydomonas reinhardtii, was isolated from rice paddy-field soil and water samples and used in the biotransformation of hydrocortisone (1). This strain has not been previously tested for steroid bioconversion. Fermentation was carried out in BG-11 medium supplemented with 0.05% substrate at 25 degrees C for 14 days of incubation.(More)
In this study a strategy based on using signal sequence and statistically optimized medium was applied for efficient extracellular production of the recombinant form of the therapeutic enzyme l-asparaginase. l-Asparaginase from E. coli is an important enzyme used in the cancer treatment, which has been produced and studied previously by other researchers.(More)
Shiga toxin B-subunit (STxB) from Shigella dysenteriae targets in vivo antigen to cancer cells, dendritic cells (DC) and B cells, which preferentially express the globotriaosylceramide (Gb3) receptor. This pivotal role has encouraged scientists to investigate fusing STxB with other clinical antigens. Due to the challenges of obtaining a functional soluble(More)
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