Mohammad Afshar

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We report the design and validation of a fast empirical function for scoring RNA-ligand interactions, and describe its implementation within RiboDock, a virtual screening system for automated flexible docking. Building on well-known protein-ligand scoring function foundations, features were added to describe the interactions of common RNA-binding functional(More)
— The paper attempts to give a formal framework to capture the entire process of scientific discovery including hypothesis formation, reasoning, identifying contradictions, peer reviewing, reformulating and so on. Data mining can be seen as one step in this complex process of interactive learning of an empirical theory This paper uses the terminology from(More)
To the best of our knowledge, this paper is the first attempt to for-malise a pragmatic logic of scientific discovery in a manner such that it can be realised by scientists assisted by machines. Using Institution Agents, we define a dialectic process to manage contradiction. This allows autoepistemic Institution Agents to learn from a supervised teaching(More)
BACKGROUND The molecular events, following ischemia and reperfusion (I/R) of the liver during transplantation are largely unknown. There is evidence that apoptotic and necrotic events may take place, and occasionally result in primary graft dysfunction. We herein report two cases, where significant I/R injury correlated with the development of liver(More)
The goal of this study was to determine the effect of topical Emu oil on the healing of burn wounds and hair follicle restoration in superficial II-degree burns in the skin of Balb/c mice. Thirty-two male Balb/c mice with burns on the back of the neck were divided into two groups: The Emu oil group received topical Emu oil twice daily, whereas the control(More)
OBJECTIVES The aim of this study was to evaluate the effects of Malva sylvestris aqueous extract on cutaneous wound healing in BALB/c mice. MATERIALS AND METHODS Twenty seven male BALB/c mice (2.5 months of age) were used. A cut wound (superficial fascia depth) was made locally. The mice were then divided into three groups: the first, second and third(More)
BACKGROUND Parkinson's disease (PD) is a common neurodegenerative disease resulting from the degeneration of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). Increasing evidence demonstrated that mice treated intranasally with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) suffered impairments in motor functions associated with(More)
INTRODUCTION University teachers are one of the main pillars of university and the quality of their performance must continuously and systematically be evaluated. This evaluation can be carried out in various ways. The aim of the present study was to survey and to compare the evaluation of faculty members in the medical school in Birjand University of(More)