Mohamed Sakel

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Hemi-spatial neglect is an attentional disorder in which the sufferer fails to acknowledge or respond to stimuli appearing in contralesional space. In recent years, it has become clear that a measurable reduction in contralesional neglect can occur during galvanic vestibular stimulation, a technique by which transmastoid, small amplitude current induces(More)
BACKGROUND/AIMS We aimed to estimate the incidence and prevalence of amyotrophic lateral sclerosis (ALS) in the South East of England. The reported incidence of ALS varies between 0.44 and 3.2 per 100,000 person years. This can partly be explained by differences in design and diagnostic criteria used. There is little population data concerning England,(More)
OBJECTIVE In recent years it has emerged that the attentional disorder of visuo-spatial neglect can be overcome via artificial stimulation of the balance system. One means of achieving this is via galvanic vestibular stimulation (GVS), a simple procedure in which tiny, electrical currents are discharged to the part of the scalp overlying the vestibular(More)
BACKGROUND Amyotrophic lateral sclerosis (ALS) is a degenerative disease of motor neurons that causes progressive paralysis and eventually results in death from respiratory failure. Environmental factors that trigger ALS might result in a pattern of geographical clustering of cases. We tested this hypothesis using the South-East England ALS population(More)
PRIMARY OBJECTIVE Galvanic vestibular stimulation (GVS) involves the delivery of small electrical current to the part of the scalp that overlies the vestibular nerves. A single, brief session transiently reduces certain types of stroke impairment with no reported side-effects. It is anticipated that further reductions will occur if the duration and(More)
PRIMARY OBJECTIVE To assess the relationship between disability, length of stay (LOS) and anticholinergic burden (ACB) with people following acquired brain or spinal cord injury. RESEARCH DESIGN A retrospective case note review assessed total rehabilitation unit admission. METHODS AND PROCEDURES Assessment of 52 consecutive patients with acquired(More)
Caloric vestibular stimulation (CVS) is commonly used to diagnose brainstem disorder but its therapeutic application is much less established. Based on the finding that CVS increases blood flow to brain structures associated with language and communication, we assessed whether the procedure has potential to relieve symptoms of post-stroke aphasia. Three(More)
OBJECTIVE To determine whether stroke patients who suffer from hemispatial neglect tend to stay in hospitals longer because they are prone to limb spasticity. DESIGN Retrospective analysis of inpatient medical notes. SETTING Inpatient neurorehabilitation unit of a regional UK teaching hospital. PARTICIPANTS All patients (N=106) admitted to the(More)
OBJECTIVE Evaluate changes in active and passive function with onabotulinumtoxinA + standard of care within goal-oriented rehabilitation programmes in adults with focal post-stroke spasticity. METHODS Prospective, 24-week double-blind study with an open-label extension. Subjects were randomized to onabotulinumtoxinA + standard of care or placebo +(More)
This paper explains the motivations and the goals of the SYSIASS project. This project has three major ambitions: to design intelligent devices for both the assisted navigation of the powered wheelchairs and the secure communication of the data and to design multi-modality human machine interaction. Moreover, the challenge of the project is to take the(More)