Mohamed Rahmani

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resistant to STI571 cells sensitive and + deacetylase inhibitors to induce apoptosis in Bcr/Abl The proteasome inhibitor bortezomib interacts synergistically with histone (4217 articles) Neoplasia (746 articles) Apoptosis Articles on similar topics can be found in the following Blood collections Information about subscriptions and ASH membership may be(More)
The potent bioactive sphingolipid mediator, sphingosine-1-phosphate (S1P), is produced by 2 sphingosine kinase isoenzymes, SphK1 and SphK2. Expression of SphK1 is up-regulated in cancers, including leukemia, and associated with cancer progression. A screen of sphingosine analogs identified (2R,3S,4E)-N-methyl-5-(4'-pentylphenyl)-2-aminopent-4-ene-1,3-diol,(More)
1 PURPOSE. Previously interferon (IFN)␥-induced apoptosis and expression of inflammation-related proteins in a human conjunctival cell line were demonstrated. The aim of this study was to further investigate the mechanisms of IFN␥-, Fas-, and cycloheximide (CHX)-induced programmed cell death, with special attention to the role of transcriptional factors(More)
In this article we present a 2D cellular automaton (Class_AC) to solve a problem of text mining in the case of unsupervised classification (clustering). Before to experiment the cellular automaton, we vectorized our data indexing textual documents from the database REUTERS 21,578 by Wordnet approach and the representation of text documents by the method(More)
The human T-cell repertoire is complex and is generated by the rearrangement of variable (V), diversity (D) and joining (J) segments on the T-cell receptor (TCR) loci. The T-cell repertoire demonstrates self-similarity in terms clonal frequencies when defined by V, D and J gene segment usage; therefore to determine whether the structural ordering of these(More)