Mohamed Marzouk

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This paper presents an automated system for optimizing earthmoving operations. The proposed system can assist earthmoving contractors, during bid preparation stage, in estimating the time and cost required in order to accomplish the task at hand. It also provides a methodology for recommending the most suitable equipment fleet that satisfies the job(More)
This paper presents a methodology that integrates fuzzy clustering and computer simulation and demonstrates its use in modeling earthmoving operations. A simulation system (<i>SimEarth</i>) was developed to model earthmoving operations utilizing object-oriented features and discrete event simulation. Fuzzy clustering is used to provide realistic estimates(More)
This paper presents an application of simulation optimization in construction utilizing genetic algorithms. The paper focuses on the use of genetic algorithms (GAs) as a tool for optimizing the total cost of earthmoving operations accounting for available equipment models to contractors and their corresponding quantities. The developed genetic algorithm has(More)
Tunnel construction are essentially infrastructure projects that includes many interfered and sophisticated tasks. This paper presents a decision support tool, <i>Tunnel_Sim</i>, for planning tunnel construction projects using computer simulation. The proposed tool assists contractors in estimating time and cost, required for the construction of tunnel(More)
This paper presents a framework (named <i>Bridge_Sim</i>) that aids contractors in planning bridge deck construction using computer simulation. The proposed framework estimates the time and cost required for construction of bridges' decks. Seven construction methods are included in the proposed framework. These are: cast-in-place on falsework, steel bridge(More)
A new series of 2-amino-benzo[de]isoquinoline-1,3-diones was synthesized and fully characterized in our previous paper. Here, their cytotoxic effects have been evaluated in vitro in relation to colon HCT-116, hepatocellular Hep-G2 and breast MCF-7 cancer cell lines, using a crystal violet viability assay. The IC50-values of the target compounds are reported(More)
BACKGROUND The persistent appearance of viral strains that causes a resistant viral infection has led to continuous trials for the design and development of novel antiviral compounds. Benzoquinazoline compounds have been reported to exhibit an interesting antiviral activity. This work aims to study and evaluate the antiviral activity of a newly prepared(More)
As part of our search for new compounds having antiviral effects, the prepared 2-aminonaphthalimide series was examined for its activity against the herpes simplex viruses HSV-1 and HSV-2. This represents the first study of the antiviral effects of this class of compounds. The new series of 2-amino-1H-benzo[de]isoquinoline-1,3-diones was examined against(More)