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Achieving high service availability is a key requirement when deploying service-based applications over ad hoc networks. Without high availability, reliable service execution cannot be achieved. Ad hoc network characteristics like ever-changing topology and limited resources are the main challenges that need to be overcome in order to achieve high(More)
BACKGROUND Bladder cancer cells illustrate major disruptions in their DNA methylation patterns as compared with normal ones. Authors aimed to identify epigenetic molecular markers in urine for early detection of bladder cancer. MATERIALS AND METHODS We retrospectively analyzed the methylation status of RARβ(2) and APC genes in urine samples from 210(More)
The problem of finding groups of co-regulated genes is considered one of the major challenges in the analysis of gene expression data. Biclustering may be considered as one of the main techniques to analyze these data. Biclustering is a non-supervised technique outperforms the traditional clustering techniques because it can group both genes and conditions(More)
Automatic discovery and invocation of services will only be accepted in practise, if the non-functional, especially QoS, parameters are taken into consideration during matchmaking. In this paper we present how this can be achieved. As an example, we use the DIANE 1 framework and explain how the concepts developed there can be extended to easily accommodate(More)
Hyaluronidase (HAase) was reported as a urinary marker of bladder cancer. In this study, a simple colorimetric gold nanoparticle (AuNP) assay was developed for rapid and sensitive detection of urinary HAase activity. Charge interaction between polyanionic hyaluronic acid (HA) and cationic AuNPs stabilized with cetyl trimethyl ammonium bromide (CTAB) led to(More)
In principle, service orientation is a suitable paradigm to allow for effective resource sharing in wireless ad hoc networks. However, special attention needs to be paid to ensure a high service availability since this is the basis for reliable service execution. Unfortunately, typical characteristics of ad hoc networks like ever-changing topology and(More)
In this paper, we argue why service-orientation is the appropriate computing paradigm to use in mobile and wireless environments. We explain how the limitations of mobile devices can be overcome by functionality sharing via service-orientation. We identify some key areas that need to be addressed in order for this vision to become a reality. We survey(More)
Endothelial dysfunction is now widely recognized as an early marker of cardiovascular disease, making its treatment, or complete avoidance, an emerging, interesting therapeutic target. This study investigated the ability of the highly intriguing amino acid L-arginine to influence endothelial function. Its therapeutic potential is also compared to that of(More)
This paper introduces a new software developed for building performance optimization. MOBO is a generic freeware able to handle single and multi-objective optimization problems with continuous and discrete variables and constraint functions. It can be coupled to many external (simulation) programs. It has a library of different types of algorithms(More)
Recently, a combination between simulation and optimisation has been important for many of HVAC design problems. Long execution time is usually needed for one simulation run; consequently huge time will be required for the optimisation process. The aim of this study is to evaluate how combinations between optimisation algorithms can achieve faster and/or(More)