Mohamed F. Salem

Rehab M Samaka1
Yahya M Naguib1
1Rehab M Samaka
1Yahya M Naguib
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BACKGROUND Acetaminophen (APAP)-induced toxicity is a predominant cause of acute hepatic and renal failure. In both humans and rodents toxicity begins with a reactive metabolite that binds to proteins. This leads to mitochondrial dysfunction and nuclear DNA fragmentation resulting in necrotic cell death. Pleurotus ostreatus (an edible oyster mushroom) is(More)
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