Mohamed El Hadi Cherifi

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Cardiac hypertrophy has been demonstrated in rat models of hyperhomocysteinemia, a major risk factor for chronic heart failure. As one of the molecular pathway which leads to cardiac hypertrophy is mediated by the serine-threonine kinase DYRK1A, we have determined the expression of Dyrk1a in the heart of hyperhomocysteinemic rats and found that(More)
In this paper we study the effect of the (mass-to-thermal) buoyancy ratio N on the interaction between gas radiation and double diffusive convection in a square cavity filled with a non-gray air-H<sub>2</sub>O mixtures at constant average concentration of H<sub>2</sub>O (13%). Uniform temperatures and concentrations are imposed along the vertical walls,(More)
Hyperhomocysteinemia, characterized by an elevated plasma homocysteine concentration, leads to several clinical manifestations and particularly cardiovascular diseases. Experimental models of hyperhomocysteinemia revealed several tissue injuries including heart fibrosis and ventricular hypertrophy. In order to analyze the molecular mechanisms link to these(More)
INTRODUCTION Elevated plasma homocysteine (Hcy) levels have been associated with several tissue injuries including heart and liver fibrosis. In these diseases, hyperhomocysteinemia (Hhcy) plays a major role in modulating the alteration of the balance between matrix metalloproteinases (MMP) and tissue inhibitors of metalloproteinases (TIMPs), leading to the(More)
A numerical study is performed to investigate the effect of the adiabatic walls emissivity on coupled double diffusive natural convection and gas radiation in a differentially heated square enclosure filled with non-gray air-H<sub>2</sub>O mixtures in a cooperating case. The vertical walls of the enclosure are maintained at two different but uniform(More)
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