Mohamed Benchekroun

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Consider a large number of interacting queues with symmetric interactions. In the asymptotic limit, the interactions between any fixed finite subcollection become negligible, and the overall effect of interactions can be replaced by an empirical rate. The evolution of each queue is given by a time inhomogeneous Markov process. This may be considered a(More)
Alzheimer's disease is a multifactorial and fatal neurodegenerative disorder characterized by decline of cholinergic function, deregulation of other neurotransmitter systems, β-amyloid fibril deposition, and β-amyloid oligomers formation. Based on the involvement of a relevant number of biological systems in Alzheimer's disease progression, multitarget(More)
We report herein the straightforward two-step synthesis and biological assessment of novel racemic benzochromenopyrimidinones as non-hepatotoxic, acetylcholinesterase inhibitors with antioxidative properties. Among them, compound 3Bb displayed a mixed-type inhibition of human acetylcholinesterase (IC50 = 1.28 ± 0.03 μM), good antioxidant activity, and also(More)
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