Learn More
Integrins are essential protagonists of the complex multi-step process of angiogenesis that has now become a major target for the development of anticancer therapies. We recently reported and characterized that MVL-PLA2, a novel phospholipase A2 from Macrovipera lebetina venom, exhibited anti-integrin activity. In this study, we show that MVL-PLA2 also(More)
Modern combustion engines are becoming increasingly complex, with more control variables, to meet the newest emissions regulations and improve the dynamic torque characteristics. However, the large number of control variables presents a challenge for the calibration process. The effects of all control variables and their interactions on the engine(More)
The last decade has obviously witnessed an emerging interest in studying human intelligence aiming to solve complex problems in many industrial fields, e.g. the process of verification and validation. Therefore, in an effort to alleviate the challenges of this process, an idea to construct intelligent test systems from the viewpoints of learning, reasoning,(More)
AahG50, the toxic fraction of Androctonus australis hector venom, was studied on human Kv3.1 channels activation, stably expressed in Xenopus oocytes using the two-electrode voltage clamp technique. AahG50 reduced Kv3.1 currents in a reversible concentration-dependent manner, with an IC50 value and a Hill coefficient of 40.4 ± 0.2 μg/ml and 1.3 ± 0.05,(More)
— Faulty software is costly and possibly life threatening as software products permeate our daily life. Therefore, the test process formulates an indispensable component of the development cycle; yet it is a formidable task. In an effort to alleviate its challenges, this contribution outlines a novel approach to enrich traditional test techniques with(More)
  • 1