Mohamed A. Taha

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OBJECTIVES To investigate the role of transforming growth factor beta(1) (TGF-beta(1)) and epidermal growth factor (EGF) in voided urine for the diagnosis and follow-up of children with pelvi-ureteric junction obstruction (PUJO). PATIENTS, SUBJECTS AND METHODS The study included 35 children with unilateral PUJO who had a pyeloplasty, and 30 healthy(More)
Genetic factors contribute to the pathogenesis of coronary artery disease (CAD). We studied 100 patients with CAD and 50 healthy individuals to assess the association of endothelial nitric oxide (eNOS) polymorphism (Glu298Asp) and angiotensinogen polymorphisms (M235T) and CAD in an Egyptian population. Serum nitric oxide (NO) and angiotensin I levels were(More)
PURPOSE We evaluated the role of voided urine lysosomal enzyme N-acetyl-beta-D-glucosaminidase and brush border enzymes alkaline phosphatase and gamma-glutamyl transferase in differentiating between children with ureteropelvic junction obstruction in need of pyeloplasty and those with dilated nonobstructed kidneys suitable for conservative treatment. (More)
The aim of this study was to design and evaluate of mucoadhesive gel formulations for the vaginal application of clomiphene citrate (CLM) for local treatment of human papilloma virus (HPV) infections. Chitosan (CHI) and polycarbophil (PC) were covalently modified using the thioglycolic acid and L-cysteine, respectively. The formation of thiol conjugates of(More)
In this study, we measured the serum concentration of TIMP-2 in patients with systemic sclerosis (SSc) and explored its possible correlation with cardiac and pulmonary lesions. We studied 42 patients with SSc, with duration equal to or more than 2 years. CT chest, ECG, echocardiography, and serum TIMP-2 concentration measurement using ELISA technique were(More)
OBJECTIVES To examine the role of voided urine endothelin-1 (ET-1) in the diagnosis and follow-up of children with ureteropelvic junction obstruction. METHODS The study included 35 children with unilateral ureteropelvic junction obstruction who underwent pyeloplasty and 30 control children, including 10 healthy children, 10 with vesicoureteral reflux, and(More)
OBJECTIVES To study the effect of pyeloplasty and conservative management on renal function in children with pelviureteral junction obstruction. METHODS This prospective study included 65 children postnatally diagnosed with unilateral pelviureteral junction obstruction. On the basis of the patients' symptoms and technetium-99m diethylenetriamine(More)
The aim of our study was to prepare clomiphene citrate gel formulations that possess appropriate mechanical properties, stay on the vaginal mucosa for a long period of time, and provide sustained drug release for the local treatment of human papilloma virus infections. In this respect, 1% CLM gels including polyacrylic acid (PAA) polymers such as Carbopol(More)
Background and Purpose: Insulin-like growth factor-1 (IGF-1) was found to have a role in both glucose homeostasis and cardiovascular disease. The present study was designed to compare the effects of fluvastatin and metformin on IGF-1 mRNA expression within the liver and on other individual components of the metabolic syndrome induced in rats by high(More)
OBJECTIVES To evaluate the role of urinary lysosomal enzyme N-acetyl-beta-D-glucosaminidase (NAG) and brush border enzymes alkaline phosphatase (ALP) and gamma-glutamyl transferase (GGT) in the long-term follow-up of children under conservative management for ureteropelvic junction narrowing. METHODS The study included 30 children with dilated(More)