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OBJECTIVE To summarize the role of reactive oxygen species (ROS) in the pathophysiology of human reproduction. DESIGN Review of literature. SETTING Fertility research center and obstetrics and gynecology department in a tertiary care facility. RESULT(S) ROS plays an essential role in the pathogenesis of many reproductive processes. In male-factor(More)
BACKGROUND Leptin influences the proinflammatory immune responses and has angiogenic activity in vitro and in vivo. The objective of this study was to evaluate the peritoneal fluid levels of leptin in patients with endometriosis and idiopathic infertility and compare them with a control group of tubal ligation/reanastomosis patients. METHODS In this(More)
The objective of this study was to compare letrozole-stimulated cycles to natural cycles in 208 patients undergoing intrauterine insemination (IUI) between July of 2004 and January of 2007. Group I (n = 47) received cycle monitoring only (natural group), Group II (n = 125) received letrozole 2.5 mg/day on cycle days three to seven, and Group III (n = 36)(More)
OBJECTIVE To examine the relationship of early human embryonic development with the level of reactive oxygen species (ROS) in the culture media on the first day (day 1 ROS) after insemination. DESIGN A prospective study. SETTING Patients undergoing assisted reproduction in a teaching hospital. PATIENT(S) Patients undergoing conventional IVF (n = 104;(More)
BACKGROUND Despite interest in cryopreservation of individual or small number of human spermatozoa, to date, little data is available as regards its effectiveness. We systematically reviewed the outcome after cryopreservation of individual or small numbers of human spermatozoa in patients with severe male factor of infertility. METHODS We searched the(More)
BACKGROUND Progesterone is a key hormonal regulator of the female reproductive system. It plays a major role to prepare the uterus for implantation and in the establishment and maintenance of pregnancy. Actions of progesterone on the uterine tissues (endometrium, myometrium and cervix) are mediated by the combined effects of two progesterone receptor (PR)(More)
OBJECTIVE To examine the relationship of early human embryonic development parameters to day 3 reactive oxygen species (D-3 ROS) levels in culture media. DESIGN Prospective study. SETTING Tertiary care hospital. PATIENT(S) Patients were undergoing IVF (n=92; 36 with intracytoplasmic sperm injection [ICSI]). INTERVENTION(S) The D-3 ROS levels in(More)
BACKGROUND To compare the clinical results and the cost-effectiveness of using the aromatase inhibitor, letrozole, in conjunction with FSH and FSH alone for controlled ovarian stimulation (COS) in patients undergoing intrauterine insemination (IUI) for a variety of indications. METHODS Four hundred and thirty-two consecutive patients who underwent 872 IUI(More)
OBJECTIVES To describe the surgical technique of robotic tubal anastomosis. METHODS Retrospective chart and video review of the instrumentation and methodology used for robotically assisted tubal anastomosis. RESULTS All tubal anastomoses were performed with the use of 3 or 4 robotic arms, 3 or 4 robotic instruments, and 1 assistant trocar. (More)
Objective. To evaluate the surgical outcomes of robotic-assisted sacrocolpopexy (RASCP) before and after the incorporation of hands-on training for urology and gynecology residents. Study Design. Forty-one patients underwent RASCP between December 2008 and March 2010 with one surgeon. RASCP was performed in the context of surgical repair of complex pelvic(More)