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BACKGROUND There are increasing evidences of endothelial dysfunction in migraine. The ACE-inhibitors have previously been shown to be effective in migraine prophylaxis. Furthermore, ACE inhibitors have beneficial effects on endothelial dysfunction. We therefore investigated whether Enalapril is effective in endothelial function improvement. METHODS In(More)
BACKGROUND Alzheimer's disease (AD) is a progressive neurodegenerative disease in which endothelial cell (EC) can be affected. In brain, functional changes in ECs contribute to reductions in resting blood flow. Furthermore, angiotensin-converting enzyme inhibitors (ACE-I) have beneficial effects on endothelial dysfunction. This is the first study that(More)
Methods In this cross-sectional study we included migraine patients based on ICHD-2 criteria from four clinics in Isfahan, Iran. HADS, HIT-6 and a symptom questionnaire were fulfilled by the patients. Each patient was asked to determine number of headache days per month (HDPM) and also headache severity by numeric rating scale (NRS). NRS is defined as a(More)
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