Mohamad Mroué

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The 4-hydroperoxycyclophosphamide (4HC)-resistant B5-180(3) subline of the cloned KBM-7/B5 cell line was developed as a model of induced cyclophosphamide resistance in human myeloid leukemia. Based on IC90 values, this subline was approximately 20-fold resistant to 4HC. Furthermore, it was significantly cross-resistant to phosphorodiamidic mustard (PM),(More)
We examined 4-hydroperoxycyclophosphamide (4HC) and phosphorodiamidic mustard (PM)-mediated cytotoxicity and DNA interstrand cross-link (ISC) induction in a 4HC-resistant subline, B5-180(3), that was derived from the subcloned human myeloid leukemia cell line KBM-7/B5. Based on the ratio of the 50% inhibitory concentration values, B5-180(3) cells were(More)
Glycerol formal (CAS 5464-28-8), an organic solvent used to vehicle drugs to target cells, has been shown to possess its own toxicopharmacological properties. The present work was undertaken to study its direct effect on the isolated rabbit heart. At 2.3 and 4.6 mmol/l (bolus) glycerol formal exerted a positive inotropic effect. Upon a perfusion of 4.5(More)
Recent fixed and mobile wireless communication systems have attracted researchers to propose new techniques and methodologies that greatly improve performance. For example, adaptive techniques have improved the wireless channel efficiency while decreasing the overall power consumption. They consist in reconfiguring parts of the global system automatically(More)
This paper presents an architecture of an IR-UWB MB-OOK non-coherent transceiver realized at Mitsubishi Electric. Channel measurements in real indoor environment based on this realized prototype are provided. The different components of this transceiver are described. A comparison between the use of directional and omnidirectional antennas at both emission(More)
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