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Hierarchical differentiation competence in response to retinoic acid ensures stem cell maintenance during mouse spermatogenesis
Stem cells ensure tissue homeostasis through the production of differentiating and self-renewing progeny. In some tissues, this is achieved by the function of a definitive stem cell niche. However,Expand
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SHISA6 Confers Resistance to Differentiation-Promoting Wnt/β-Catenin Signaling in Mouse Spermatogenic Stem Cells
Summary In the seminiferous tubules of mouse testes, a population of glial cell line-derived neurotrophic factor family receptor alpha 1 (GFRα1)-positive spermatogonia harbors the stem cellExpand
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Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche
Summary In many tissues, homeostasis is maintained by physical contact between stem cells and an anatomically defined niche. However, how stem cell homeostasis is achieved in environments where cellsExpand
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