Mobeen Iqbal

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In 120 patients with severe emphysema evaluated for participation in the National Emphysema Treatment Trial, pulmonary hemodynamics and ventricular function were assessed. Pulmonary function tests were (%predicted): FEV(1) = 27%; residual volume = 224.6%; diffusion capacity = 26.7%. In 90.8% of patients, end-expiratory pulmonary artery mean pressure was >(More)
OBJECTIVES To determine the time course for myocardial production of nitric oxide, peroxynitrite, and glutathione, to determine the activities of the myocardial antioxidant enzymes glutathione peroxidase, superoxide dismutase, and glutathione reductase throughout endotoxemia and into recovery, and to correlate the levels of these variables to left(More)
BACKGROUND Characterization of pleural effusion into an exudate or transudate is usually the first step in diagnostic evaluation. Light's criteria have been universally accepted as gold standard in this regard. We wanted to see the utility of isolated pleural fluid lactic dehydrogenase level (representing one of Light's classical criteria) in characterizing(More)
OBJECTIVE To study the efficacy of nurse-driven intensive glucose management protocol in an intensive care setting. METHODS This cohort study took place at King Abdul-Aziz National Guard Hospital, Al-Hasa, Saudi Arabia from April 2005 through June 2005. We modified a validated nurse-driven glycemic protocol when glucose level was >11.1 mmol/L. Protocol(More)
OBJECTIVE To determine the efficacy and safety of Total Dose Infusion (TDI) of low molecular weight iron dextran for the treatment of iron deficiency anemia compared to oral iron replacement during pregnancy through improvement in hemoglobin (Hb) after intervention. STUDY DESIGN Non-randomized control trial. PLACE AND DURATION OF STUDY Section of(More)
BACKGROUND The severity of bronchial asthma has been associated with increased body mass index (BMI) in several studies. We studied obesity in the asthmatic population and its possible correlation with spirometric variables. METHODS We reviewed the medical records of 200 patients who underwent spirometry and were followed up in a pulmonary clinic for(More)
OBJECTIVE We assessed the safety and complications related to percutaneous tracheostomy (PCT) without bronchoscopic guidance in our intensive care unit (ICU). METHODS The prospective data over a period of 24 months were collected for patients who underwent PCT. Major, minor and long-term complications were recorded. The parameters recorded were: age,(More)
Whole lung lavage is still the most effective treatment for pulmonary alveolar proteinosis. We report a 21-year-old male diagnosed with pulmonary alveolar proteinosis by open lung biopsy and who underwent whole lung lavage with a modified technique. He showed significant improvement in clinical and functional parameters. The technique of intermittent double(More)
Evidence-based Medicine (EBM) is the process of systematically reviewing, appraising and using clinical research findings to aid the delivery of optimal clinical care to patients. EBM has become popular due to: the need for valid information about diagnosis, prognosis, therapy and prevention during patient care; traditional sources such as textbooks and(More)
OBJECTIVE To demonstrate that evidence-based medicine (EBM) training can be imparted in developing countries using minimal resources. DESIGN Development of a minimal cost workshop with validation of gain in EBM skills using the Berlin questionnaire. SETTING Teaching hospital in Pakistan. PARTICIPANTS Multidisciplinary faculty from The Shifa College of(More)