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The present study was aimed to investigate and compare the efficacy of duloxetine (DLX) loaded nanostructured lipid carriers (NLC) with DLX solution pharmacodynamically following intranasal administration. The study was further conducted to estimate DLX concentration in brain and blood. DLX was administered to albino Wistar rats either intranasally or(More)
Peripheral plasma levels of immunoreactive 6-oxo-PGF1 alpha, the stable hydrolysis product of prostacyclin, were significantly higher in female patients with tumours of the genital tract than in normal controls. In the groups with malignant tumours, these high levels declined after operation and/or radiotherapy if the tumour responded to treatment. In(More)
Tumors of the parotid glands are believed to represent approximately 2% of tumors of the head and neck. Parotid gland tumors also accounts for 70% to 80% of all tumors of the salivary glands. 1 Approximately, 80% of parotid tumors are benign and 80% of benign tumours are pleomorphic adenomas and 80% arise from the superficial lobe of the parotid gland. 2(More)
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