Miyoko Hirasawa

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We examined the effect of patient-controlled intravenous analgesia (PCIA) using metoclopramide hydrochloride and morphine hydrochloride in 30 patients (15 males, 15 females) who underwent spine fusion surgery under general anesthesia. The intravenous administration of 2 mg morphine hydrochloride was done prior to the completion of surgery. Subsequently,(More)
Forty thymomas and thymic carcinomas were classified in terms of WHO histologic typing, Masaoka staging system, and p53 expression. In WHO histologic typing, type A, AB, B1, B2, B3, and C were 1, 10, 16, 5, 4, and 4 cases, respectively. In Masaoka staging system, I, II, III, and IV were 15, 9, 10, and 6 cases, respectively. Thirteen thymomas exhibited(More)
Twelve patients who suffered from low grade malignant tumors arisen in the trachea and the bronchus (6 of carcinoid, 4 of mucoepidermoid carcinoma, and 2 of adenoid cystic carcinoma) underwent surgical treatment from 1977 to 1996 in our department. Operations included 1 sleeve resection of the trachea, 1 patch plasty of the trachea, 3 sleeve lobectomies,(More)
The goal of this retrospective study was to evaluate the effects of perioperative administration of sivelestat sodium hydrate, a selective neutrophil elastase inhibitor, on the clinical course after radical surgery for esophageal cancer. The effects of sivelestat on postoperative systemic inflammatory reactions and respiratory function were examined in 53(More)
BACKGROUND Enhancement of re-endothelialization inhibits the progression of intimal hyperplasia. We investigated uptake of Lipoprostaglandin E(1) (LPGE(1)) by endothelial cells (ECs) and vascular smooth muscle cells (VSMCs), and effects of the LPGE(1) on re-endothelialization of vein grafts. METHODS Primary cultured ECs and VSMCs were obtained from(More)