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Pleomorphic carcinoma (PC) of the lung is rare, and it is classified as a subtype of sarcomatoid carcinoma of the lung in the World Health Organization histologic classification of lung tumors. In this study, 70 cases of PC surgically resected were reviewed to identify its clinicopathologic characteristics. There were 57 men and 13 women, and their mean age(More)
OBJECTIVE The aim of this study was to analyze intraoperative pleural lavage cytology results in patients with non-small-cell lung cancer and quantify the impact on survival and recurrence. METHODS From August 1992 through November 2006, pleural lavage cytology results before and after lung resection were both available in 2178 patients with(More)
INTRODUCTION From 1998 to 2002, we performed a trial of prospective limited resection for pulmonary ground-glass opacity lesions 2 cm or smaller. This is the second report on the long-term outcome. METHODS The enrollment criteria of the trial were as follows: pulmonary peripheral nodule less than 2 cm, diagnosis or suspected diagnosis of clinical T1N0M0(More)
BACKGROUND Although postoperative morbidity and mortality rates in patients with lung cancer have decreased with advances in perioperative management, those patients with idiopathic pulmonary fibrosis (IPF) remain at a high risk of complication and death. The frequency of postoperative morbidity and mortality rates in patients with lung cancer who have IPF(More)
BACKGROUND Thoracoscopic esophagectomy in the prone position (TSEP) without thoracotomy is more invasive than right transthoracic esophagectomy (TTE). However, TTE and TSEP have not been compared in terms of technical and oncological feasibility for thoracic esophageal carcinomas of the same stage. METHODS Fifty-nine patients with clinical stage I(More)
OBJECTIVE Although visceral pleural invasion by non-small cell lung cancer is considered a poor-prognostic factor, further information is lacking, especially in relation to other clinicopathologic prognostic factors. We assessed the relationship between visceral pleural invasion and other clinicopathologic characteristics and evaluated its significance as a(More)
BACKGROUND Cancer-associated fibroblasts (CAFs) directly communicate with cancer cells and play important roles in cancer progression. Recent studies have reported that primary cancer tissue with podoplanin-expressing CAFs predicted a poorer outcome among stage I lung adenocarcinoma patients. However, whether podoplanin(+)-CAFs also can be recruited into(More)
A 66-year-old man presented with severe back pain. Imaging studies revealed a well-circumscribed mass in the left posterior mediastinum. Because of pleural dissemination observed at thoracotomy, palliative resection was performed to relieve his back pain. Histologically, the tumor was composed of cells with large eosinophilic and granular cytoplasm, which(More)
BACKGROUND Invasive micropapillary carcinoma has been recognized as a rare disease entity with aggressive tumor behavior. However, few reports have described invasive micropapillary carcinoma in the gastrointestinal tract, particularly its involvement in gastric cancer. METHODS We retrospectively analyzed 930 patients diagnosed with gastric cancer who(More)
Extraskeletal osteosarcoma arising from the mediastinum is an extremely rare malignant tumor. We present the case of a 77-year-old woman with a past history of pulmonary tuberculosis who presented with a dyspnea. Imaging studies revealed a huge anterior mediastinal mass with scattered calcifications. Complete surgical resection was successfully performed,(More)