Mitsutoshi Ito

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The present study was performed to clarify whether or not structural plasticity of synaptic connections underlies classical conditioning mediated by the red nucleus (RN) in the cat. Conditioned forelimb flexion is established by pairing electrical conditioned stimuli (CS), applied to corticorubral fibers at the cerebral peduncle (CP), with a forelimb skin(More)
1.) By extracellular and intracellular recordings of the red nucleus (RN) cell activity, we investigated enhancement of signaling effectiveness at the cortico-rubral synapses underlying the establishment of classical conditioning mediated by RN in the cat. The classical conditioning of forelimb flexion was produced by pairing the conditioned stimulus (CS)(More)
The average latency of cortical neuronal responses to electrical optic nerve (ON) stimulation was 3.0 +/- 0.7 s.d. msec. No significant difference between latencies to ipsi- and contralateral ON stimulation was found. Binocularly excitable cells showed almost equal response latencies to stimulation of both nerves. The average latency of subcortically(More)
A small lesion was placed in the rat somatosensory vibrissa cortex on postnatal days (PND) 0, 5, 10, 14 or 20. At the age of three months, the animals were sacrificed and tangential sections of the somatosensory cortex were reacted for detection of succinic dehydrogenase or cytochrome oxidase activity to see if the lesion had produced a defect in the(More)
AIM Pregabalin (PGB), a drug used for treating neuropathic pain, has immune--modulating property that may have therapeutic implications. Suppression of microglial activation and improvement in functional recovery was observed in experimental spinal cord injury after PGB administration. An experimental study was conducted to evaluate whether PGB could afford(More)
PURPOSE To evaluate the efficacy and safety of conductive keratoplasty (CK) for the treatment of presbyopia and analyze the differences in the effects between post- and non-laser in situ keratomileusis (LASIK) eyes. Clinical preoperative factors that could affect the predictability of CK were also analyzed. METHODS The visual and refractive outcomes of CK(More)
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