Mitsuru Nakata

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The purpose of this paper is to discuss how to model and analyze signaling pathways by using Petri net. Firstly, we propose a modeling method based on Petri net by paying attention to the molecular interactions and mechanisms. Then, we introduce a new notion "activation transduction component" in order to describe an enzymic activation process of reactions(More)
This paper first presents basic Petri net components representing molecular interactions and mechanisms of signalling pathways, and introduces a method to construct a Petri net model of a signalling pathway with these components. Then a simulation method of determining the delay time of transitions, by using timed Petri nets - i.e. the time taken in fi ring(More)
In traditional Chinese medicine, internal organs imply five viscera and six bowels. Five viscera mean liver, heart, spleen, lung and kidney, and six bowels mean gallbladder, small intestine, stomach, large intestine, urinary bladder and triple energizer. Also, meridian system represents the passage of metabolites in the human body. In this paper, we deal(More)