Mitsuru Honda

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Subarachnoid hemorrhage (SAH) causes dynamic changes in cerebral blood flow (CBF), and results in delayed ischemia due to vasospasm, and early perfusion deficits before delayed cerebral vasospasm (CVS). The present study examined the severity of cerebral circulatory disturbance during the early phase before delayed CVS and whether it can be used to predict(More)
Traumatic brain injury (TBI) is widely known to cause dynamic changes in cerebral blood flow (CBF). Ischemia is a common and deleterious secondary injury following TBI. Detecting early ischemia in TBI patients is important to prevent further advancement and deterioration of the brain tissue. The purpose of this study was to clarify the cerebral circulatory(More)
INTRODUCTION Traumatic brain injury (TBI) is widely known to cause dynamic changes in cerebral blood flow (CBF). In particular, secondary brain insults have been reported to decrease CBF. The purpose of this study was to clarify the cerebral circulation in different types of TBI. METHODS Sixty-nine patients with TBI were divided into four groups, the(More)
OBJECTIVE The purpose of this study was to clarify the difference between cerebral blood flow (CBF) by perfusion computed tomography (CT) and that by xenon-enhanced CT (Xe-CT) through simultaneous measurement. METHODS Xenon-enhanced CT and perfusion CT were continually performed on 7 normal subjects. Ratios of CBF by perfusion CT (P-CBF) to CBF by Xe-CT(More)
The objective of this work is to propose a quantitative cerebral blood flow (CBF) calculation method for xenon CT (Xe-CT) by logically estimating the time course change rate (rate constant) of the arterial xenon concentration from that of end-tidal xenon concentration. A single factor, gamma (gamma), which is considered to reflect the diffusing capacity of(More)
AIMS Neurointensive care has reduced the mortality and improved the outcome of patients for severe brain damage, over recent decades, and made it possible to perform this therapy in safety. However, we have to understand the complications of this therapy well. The purpose of our study was to determine the systemic circulation disturbance during the(More)
A novel model for collimation and transport of electron-positron-ion jets is presented. Analytical results show that the filamentary structures can be sustained by self-induced toroidal magnetic fields permeating through the filaments, whose widths significantly expand in the pair-dominant regimes. The magnetic field strength reflects a characteristic of(More)
BACKGROUND Only a few approved drugs are capable of alleviating the cognitive and behavioural symptoms of people living with Alzheimer's disease (AD). In recent years, however, the number of studies examining the clinical effects of herbal medicines on cognitive function in patients with AD has increased considerably. This study evaluated the long-term(More)
We propose a modified version of the X-ray spectral index and an intrinsic cutoff frequency of inverse Compton radiation from the brightest knot of the M87 jet, in conjunction with an application of the new conceptions of injection and diffusive shock acceleration (DSA) of electrons in magnetized filamentary plasma, to the specified source. The drop of the(More)