Mitsuo Kimura

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Theoretical studies have focused on the environmental temperature of the universal common ancestor of life with conflicting conclusions. Here we provide experimental support for the existence of a thermophilic universal common ancestor. We present the thermal stabilities and catalytic efficiencies of nucleoside diphosphate kinases (NDK), designed using the(More)
The course and prognosis of 308 patients with ulcerative colitis who visited Tohoku University Hospital during the period from 1954 to 1987 were investigated. Based these investigations, the following results were obtained. 1) In 27.6% of patients with proctitis, extension to the proximal colon developed during the observation period. 2) Surgical(More)
Endothelial leucocyte adhesion molecule-1 (ELAM-1) is a rapidly inducible adhesion molecule for neutrophils in vascular endothelial cells. We investigated its immunohistochemical localization in 17 cases of inflammatory bowel disease. ELAM-1 was preferentially expressed in venules in actively inflamed mucosa and granulation tissue. Most capillaries were(More)
PHRENIC NERVE stimulators for diaphragm pacing have been described by a number of workers (e.g. GLENN et al., 1980; 1984; TALONEN et al., 1983; HOSHIMIYA et al., 1976). As for cardiac pacemakers, many that can control the heart rate in compliance with the patient's physiological needs have been developed (e.g. GEDDES et al., 1984). However, almost every(More)
[reaction: see text] Phosphates from 3-substituted 4,4,4-trifluorobut-2-en-1-ols were found to be effective for construction of CF3-containing quaternary carbon centers by way of Cu(I)-catalyzed Grignard reactions in the presence of catalytic amounts of CuCN and trimethylsilyl chloride (TMSCl) in an anti S(N)2' manner.
tokardiographische Untersuchungen. Wehrmed., 6, 102-104. BURKHART, K., SEIPEL, Lo and KIRCHHOFF, H. W. (1969) Neuere Untersuchungen fiber haemodynamische Vorg/inge in der Ballistokardiographie. Z. Kreislaufforschuno, 58, 266-277. CUNNINGnAM, D. M. and SMILEr, P. C. (1961) A hydrostatic air-bearing ballistocardiograph. J. Appl. Physiol., 16, 755-758. DOCK,(More)
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