Mitsunobu Miyagi

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BACKGROUND Interleukin-1 (IL-1) is a potent mediator of inflammation and is known to induce bone resorption. We studied the effects of sex hormones on the function of human monocytes and demonstrated that prostaglandin E2 (PGE2) production was enhanced by progesterone and estradiol. As PGE2 has been shown to suppress the production of IL-1 by monocytes, it(More)
The effects of sex hormones on the vitro production of prostaglandin (PG) E2 by monocytes were investigated. Monocytes were obtained from heparinized peripheral blood of healthy adults and incubated for 24 hours with lipopolysaccharide (LPS) and sex hormones. After incubation, the medium was assayed for PGE2 by means of radioimmunoassay. PGE2 production by(More)
The effects of sex hormones on the in vitro chemotaxis of polymorphonuclear leukocytes (PMNs) and monocytes were investigated using fMLP as the chemoattractant. PMNs, monocytes, and plasma were obtained from heparinized peripheral blood of healthy adults. Chemotaxis of PMNs or monocytes treated with sex hormones were tested using 48-well chemotaxis(More)
OBJECTIVE The objective of this study was to compare the bactericidal effect of the Er:YAG (wavelength 2.94 microm) and the Alexandrite (wavelength 0.75 microm) laser radiation. The spreading laser energy in the surrounding hard dental tissues round the root canal was evaluated and the bactericidal effect of both these different laser wavelengths was(More)
A hollow fiber composed of a glass capillary tube and a metal thin film upon the inside of the tube is proposed for the delivery of ArF-excimer laser light. From theoretical analysis, aluminum is chosen as the metal layer. A thin aluminum film is deposited by metallorganic chemical-vapor deposition, with dimethylethylamine alane employed as the source(More)
Pulse spreading in a single-mode optical fiber is discussed taking into account the third-order dispersion term of the waveguide when the light source is modulated by a Gaussian pulse. A general expression for the pulse shape is analytically obtained, and an asymptotic approximation is used when the third-order dispersion term is small. It is also shown(More)
Flexible hollow fibers for delivery of the second, third, and fourth harmonic pulses of Q-switched Nd:YAG lasers are introduced. For the doubled (532-nm) wavelength, we fabricated a hollow fiber with an internal metal and polymer film by using a silver-mirror plating and a liquid-phase-coating method. For tripled (355-nm) and quadrupled (266-nm) Nd:YAG in(More)
Basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) have shown strong angiogenetic effects in ischemic animals; however, whether such a beneficial effect could be achieved using low doses remains to be determined. The effects of identical low-level doses of these substances on the creation of collateral circulation in canine(More)
This study describes a preclinical investigation with laser-activated bleaching agent for discolored teeth. Bleaching techniques involve a broad-spectrum approach utilizing hydrogen peroxide (3-38%) with or without heat or laser, carbamide peroxide (10-30%), or a mixture of sodium perborate and hydrogen peroxide. Extracted human maxillary central incisors(More)
Cyclic olefin polymer (COP) is newly used as the inner dielectric of infrared, hollow glass waveguides because of its low extinction coefficient in the mid-infrared region. A liquid-flow coating and dry-cure process are employed to form the COP layer on the inside of a silver-coated hollow glass tube. In the coating process, cyclohexane is chosen as the(More)