Mitsumasa Sudo

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Periprocedural myocardial infarction (PMI) is one of the major complications of percutaneous coronary intervention (PCI). We investigated the influence of coronary plaque burden and characteristics on PMI using intravascular ultrasound (IVUS) with radiofrequency-based tissue characterization technology (iMAP). The study population consisted of 33(More)
BACKGROUND Although clinical trials have proved that statin can be used prophylactically against cardiovascular events, the direct effects of statin on plaque development are not well understood. We generated low-density lipoprotein receptor knockout (LDLR(-/-)) pigs to study the effects of early statin administration on development of atherosclerotic(More)
Patients with acute coronary syndrome (ACS) are thought to have multiple vulnerable coronary plaques. We analyzed non-culprit plaques in patients with ACS vs. stable angina pectoris (SAP) by means of color-coded intravascular ultrasound (iMap-IVUS). Patients who underwent percutaneous coronary intervention were divided into an ACS group (n = 39) and an SAP(More)
BACKGROUND AND AIMS Glucagon-like peptide-1 (GLP-1) is thought to inhibit development of aortic atherosclerosis and plaque formation. However, whether GLP-1 stabilizes fully developed atherosclerotic plaque or alters the complicated plaque composition remains unclarified. METHODS Ten Watanabe heritable hyperlipidemic (WHHL) rabbits were divided into GLP-1(More)
BACKGROUND To examine the effects of pitavastatin on atherosclerotic plaque in Watanabe heritable hyperlipidemic (WHHL) rabbits using serial in vivo tissue-characterizing intravascular ultrasound. METHODS A total of 11 WHHL rabbits of 10-12 weeks of age were divided into two groups, control and pitavastatin-administered groups. A total of 29(More)
A fter bare-metal stent implantation, very late stent thrombosis (VLST) is considered to be rare. The most frequent cause of VLST is neointimal plaque rupture (1). Some previous reports with using a single imaging device have revealed that it is based on atheromatous changes of the neointima (2). However, it has not been fully clarified why an in-stent(More)
Anti-platelet therapy is well known to reduce coronary events such as mortality, myocardial infarction and improving the prognosis in patients with coronary artery disease. In addition, dual antiplatelet therapy(DAPT) using aspirin and thienopyridine (usually clopidogrel) is a standard regimen after stenting as one of the standard therapy of(More)
AIM Epicardial adipose tissue (EAT) is implicated in the development of coronary atherosclerosis.We sought to investigate the association between the EAT thickness and presence of multivessel disease (MV) in patients with acute myocardial infarction (AMI). METHODS We enrolled 45 consecutive patients with AMI who underwent primary percutaneous coronary(More)
OBJECTIVE Although the plaque characteristics have been recognized in patients with acute myocardial infarction (AMI), the plaque spatial distribution is not well clarified. Using color-mapping intravascular ultrasound (iMAP-IVUS), we examined culprit lesions to clarify plaque morphology, composition and spatial distribution of the sites of potential(More)
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