Mitsuhiro Tsuura

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BACKGROUND AND PURPOSE The present study was designed to determine the effect of nitro-L-arginine, the inhibitor of nitric oxide synthesis, on the evolution of cytotoxic brain edema during focal cerebral ischemia. METHOD Diffusion-weighted and contrast-enhanced, perfusion-sensitive magnetic resonance imaging was performed in anesthetized, mechanically(More)
A carotid embolic stroke model in rats was studied with a combination of diffusion- and perfusion-sensitive magnetic resonance (MR) imaging at 4.7 T. Capillary blood deoxygenation changes were monitored during formation of focal ischemia by acquiring multisection magnetic susceptibility-weighted echo-planar images. A signal intensity decrease of 7% +/- 3 in(More)
BACKGROUND AND PURPOSE The literature contains relatively few reports of distal embolism associated with intervention for intracranial atherosclerotic disease. Our purpose was to evaluate the frequency of thromboembolic events after percutaneous transluminal angioplasty (PTA) or stent placement in this setting by using diffusion-weighted (DW) imaging. (More)
We compared the anatomic extent and severity of ischemic brain injury shown on diffusion-weighted magnetic resonance (MR) images, with cerebral tissue perfusion deficits demonstrated by a nonionic intravascular T2*-shortening magnetic susceptibility contrast agent used in conjunction with standard T2-weighted spin-echo and gradient-echo echo-planar images.(More)
  • M Tsuura
  • Nō to shinkei = Brain and nerve
  • 1996
To determine whether intracerebral distribution of clot emboli can induce perfusion deficits and ischemic brain injury in a rat embolism model, diffusion/perfusion magnetic resonance imaging techniques were employed using a 4.7 Tesla imager. Clot emboli produced from venous blood were injected into the right internal carotid artery of male Sprague-Dawley(More)
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