Mitsuhiro Hishida

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Patients with hepatocellular carcinoma (HCC) have a poor prognosis, and novel molecular targets for treating recurrence and progression of the disease along with associated biomarkers are urgently required. In the present study, expression and the regulatory mechanism of TUSC1 (tumor suppressor candidate 1) were investigated to determine if it is a(More)
BACKGROUND To identify genes associated with hepatocellular carcinoma (HCC) pathogenesis, we developed a triple combination array strategy comprising methylation, gene expression, and single nucleotide polymorphism (SNP) array analysis. METHODS Surgical specimens obtained from a 68-year-old female HCC patient were analyzed by triple combination array, and(More)
BACKGROUND To detect genes correlated with hepatocellular carcinoma (HCC), we developed a triple combination array consisting of methylation array, gene expression array and single nucleotide polymorphism (SNP) array analysis. METHODS A surgical specimen obtained from a 68-year-old female HCC patient was analyzed by triple combination array, which(More)
Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related death especially among Asian and African populations. It is urgent that we identify carcinogenesis-related genes to establish an innovative treatment strategy for this disease. Triple-combination array analysis was performed using one pair each of HCC and noncancerous liver samples(More)
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