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The purpose of this study was to investigate the effects of probiotic and conventional yogurt on the lipid profile in type 2 diabetic people. In a randomized double-blind controlled trial, 60 people (23 males and 37 females) with type 2 diabetes and low-density lipoprotein cholesterol (LDL-C) greater than 2.6 mmol/L were assigned to 2 groups. Participants(More)
OBJECTIVE Oxidative stress plays a major role in the pathogenesis and progression of diabetes. Among various functional foods with an antioxidant effect, probiotic foods have been reported to repress oxidative stress. The objective of this clinical trial was to assess the effects of probiotic and conventional yogurt on blood glucose and antioxidant status(More)
Metformin is the only biguanide oral hypoglycemic drug, that is used to treat patients with type-2 diabetes mellitus. There are some reports of metformin being associated with decreased serum levels of vitamin B12 (VB12). The objective of this study is to systematically analyze the impact of metformin on the frequency of VB12 deficiency and serum levels of(More)
OBJECTIVE To examine the role of adiponectin as a biomarker of insulin resistance in polycystic ovary syndrome (PCOS). BACKGROUND PCOS is associated with metabolic syndrome, which correlates to increased cardiovascular risk in these patients. Adiponectin is decreased in obese individuals. METHODS Ninety women with PCOS (45 with and 45 without metabolic(More)
Glucagon-like peptides receptor agonists are currently approved as anti-obesity agents, yet the experience with their use in polycystic ovarian syndromes (PCOS)-related obesity and insulin resistance is still limited. We examined the effects of liraglutide on obesity, insulin resistance, and androgen levels in PCOS through a meta-analysis. Seven RCTs where(More)
BACKGROUND AND OBJECTIVES Iron overload is a major problem in patients with beta-thalassemia major, and it has many structural and metabolic consequences. The aim of this study was evaluation of endocrine disturbances in patients with beta-thalassemia major who were older than 10 years of age. PATIENTS AND METHODS In this cross-sectional study,(More)
Thyroid diseases may cause signs and symptoms of neuromuscular dysfunction. Hypothyroidism has been associated with the clinical features of proximal muscle weakness, mononeuropathy, and sensorimotor polyneuropathy. This study aimed at evaluating the electrophysiologic findings in patients with untreated spontaneous hypothyroidism and comparing them with a(More)
AIM Hypertension and overweight are prevalent problems in type 2 diabetic patients. The purpose of this study was to assess the effects of long term regular aerobic exercise training on blood pressure (BP) as well as body mass index (BMI) in type 2 diabetes mellitus (T2DM). METHODS In a randomized, controlled trial, 60 patients with T2DM aged 40-65 years(More)
INTRODUCTION Metabolic acidosis confirmed by arterial blood gas (ABG) analysis is one of the diagnostic criteria for diabetic ketoacidosis (DKA). Given the direct relationship between end-tidal carbon dioxide (ETCO2), arterial carbon dioxide (PaCO2), and metabolic acidosis, measuring ETCO2 may serve as a surrogate for ABG in the assessment of possible DKA.(More)
BACKGROUND Hypoventilation is a frequently suspected complication of hypothyroidism. OBJECTIVE In this study we examined the hypothesis that changes in alveolar ventilation, as measured by end-tidal carbon dioxide (Et-CO(2)), differ between patients with mild (subclinical) and overt (clinical) thyroid hormone deficiency, and both differ from healthy(More)