Mitchell Shnier

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The first South African case of haemolytic anaemia due to erythrocyte pyrimidine 5'-nucleotidase deficiency is reported. The anaemia is characterized by the presence of high erythrocyte pyrimidine nucleotide levels and marked basophilic stippling. The enzyme levels in 20 family members confirm an autosomal recessive mode of inheritance and illustrate the(More)
The Wenckebach type of heart block is characterized by a progressive lengthening of the P-R interval until A.V. conduction fails and a beat is dropped. This fornm of heart block was first described as a clinical entity by Wenckebach (1899) on the basis of radial arteriograms. Since then, this phenomenon has been seen in a variety of conditions including(More)