• Publications
  • Influence
Introductions and early spread of SARS-CoV-2 in the New York City area
New York City (NYC) has emerged as one of the epicenters of the current SARS-CoV2 pandemic. To identify the early events underlying the rapid spread of the virus in the NYC metropolitan area, weExpand
  • 94
  • 7
Abnormal glycogen chain length pattern, not hyperphosphorylation, is critical in Lafora disease
Lafora disease (LD) is a fatal progressive epilepsy essentially caused by loss‐of‐function mutations in the glycogen phosphatase laforin or the ubiquitin E3 ligase malin. Glycogen in LD isExpand
  • 29
  • 2
  • PDF
Nature of alpha and beta particles in glycogen using molecular size distributions.
Glycogen is a randomly hyperbranched glucose polymer. Complex branched polymers have two structural levels: individual branches and the way these branches are linked. Liver glycogen has a thirdExpand
  • 54
  • 1
Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment.
Glycogenin is considered essential for glycogen synthesis, as it acts as a primer for the initiation of the polysaccharide chain. Against expectations, glycogenin-deficient mice (Gyg KO) accumulateExpand
  • 31
  • 1
Extraction, isolation and characterisation of phytoglycogen from su-1 maize leaves and grain.
Phytoglycogen is a highly branched soluble α-glucan found in plants, particularly those with decreased activity of isoamylase-type starch debranching enzyme, such as sugary-1 (su-1) maize. AnExpand
  • 26
  • 1
The molecular size distribution of glycogen and its relevance to diabetes
Glycogen is a highly branched polymer of glucose, functioning as a blood-glucose buffer. It comprises relatively small β-particles, which may be joined as larger aggregate α-particles. The sizeExpand
  • 8
  • 1
  • PDF
Angelica sinensis polysaccharide protects against acetaminophen-induced acute liver injury and cell death by suppressing oxidative stress and hepatic apoptosis in vivo and in vitro.
  • P. Cao, Jinlu Sun, +5 authors K. Wang
  • Chemistry, Medicine
  • International journal of biological…
  • 19 February 2018
Acetaminophen (APAP)-induced hepatic damage is prevalent in western countries. The present study aimed to investigate the hepatoprotective effects of Angelica sinensis polysaccharide (ASP), an activeExpand
  • 28
The structure of cardiac glycogen in healthy mice.
Transmission electron micrographs of glycogen extracted from healthy mouse hearts reveal aggregate structures around 133 nm in diameter. These structures are similar to, but on average somewhatExpand
  • 26
Changes in glycogen structure over feeding cycle sheds new light on blood-glucose control.
Liver glycogen, a highly branched polymer of glucose, is important for maintaining blood-glucose homeostasis. It was recently shown that db/db mice, a model for Type 2 diabetes, are unable to formExpand
  • 35
Molecular structure of glycogen in diabetic liver
Liver glycogen (involved in maintaining blood-sugar levels) is a hyperbranched glucose polymer containing β particles (diameter ~20 nm), which can form composite α particles (diameter ~50–300 nm),Expand
  • 26