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Current knowledge of the multifunctional 17β-hydroxysteroid dehydrogenase type 1 (HSD17B1).
At the late 1940s, 17β-HSD1 was discovered as the first member of the 17β-HSD family with its gene cloned. The three-dimensional structure of human 17β-HSD1 is the first example of any human steroid… Expand
Identification of novel potent inhibitors against Bcl-xL anti-apoptotic protein using docking studies.
- G. Shipra, Misra Gauri, Pant Mohan Chandra, Seth Prahlad Kishore
- Medicine, Biology
- Protein and peptide letters
- 30 November 2012
Bcl-xL protein belongs to BCL-2 family which has either pro- or anti-apoptotic activities owing to their importance in the regulation of apoptosis, tumor genesis and cellular responses to anti-cancer… Expand