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OBJECTIVE To detect differences in follicular fluid (FF) levels of amphiregulin (AR), depending on mode of triggering final oocyte maturation. DESIGN Prospective randomized trial. SETTING Three IVF units. PATIENT(S) Ninety-six patients undergoing IVF-intracytoplasmic sperm injection. INTERVENTION(S) Ovulation triggered with either urinary hCG or(More)
The present study assessed whether the smoking habits of fathers around the time of conception affected the period in which daughters experienced menstrual cycles (i.e., the reproductive life span). The study revealed that the smoking habits of the farther shortened the daughters' reproductive life span compared with daughters whose fathers did not smoke.
We assessed whether the smoking habits of parents around the time of conception affects the likelihood of the offspring being male or female. We found that the offspring sex ratio (male to female) was lower when either one or both of the parents smoked more than 20 cigarettes per day compared with couples in which neither of the parents smoked. We found the(More)
The aim of this study was to evaluate whether frequency of ovulation and fertility potential of oocytes from the two ovaries differed in regularly menstruating women (1057 cycles of 856 fertile women and 1033 cycles of 258 infertile women). For both fertile and infertile women ovulation from the right ovary occurred more often than from the left ovary (55(More)
OBJECTIVE To compare IVF and pregnancy outcomes before and after anovulation induced by oral contraceptives. DESIGN Observational clinical study. SETTING Infertility clinic. PATIENT(S) Forty women with two intact ovaries (32 of 40 couples with male factor infertility and 8 with unknown causes of infertility) underwent 190 IVF treatment cycles (55(More)
Identification of the ovary from which ovulation takes place in two consecutive menstrual cycles results in one of four ovulation patterns, contralateral and ipsilateral ovulations on the right or on the left ovary. Our data suggest that IVF and IUI treatment in cycles in which development of the dominant follicle occurs in the right-sided ovary--and(More)
BACKGROUND The aim of this study was to evaluate whether characteristics of human ovulation correlate with age and pregnancy potential. METHODS Two groups of women with regular menstrual cycles were included (i.e. one fertile and one infertile group), which were divided into four age groups (< or =29, 30-34, 35-39, > or = 40 years). Monitoring included(More)
OBJECTIVE To evaluate whether climate change is associated with male:female ratios (sex ratios) of fetal deaths and births in Japan. DESIGN A population-based cohort study. SETTING Not applicable. PATIENT(S) Newborn infants and fetuses spontaneously aborted after 12 weeks of gestation. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Yearly sex(More)
BACKGROUND Early menarcheal age is a risk factor for breast and ovarian cancers and is also associated with an increased spontaneous abortion rate. The aim of this study was to investigate whether there is a link between early menarcheal age and the offspring sex ratio. METHODS We recorded the sex of 21208 live born infants, all singletons, born to 10 847(More)