Mirthula Govindaraj

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Twenty patients with extrinsic type bronchial asthma are shown to have a significant fall in vital capacity (V.C.) and forced expiratory volume in 1 second (F.E.V.(1)) after an intravenous infusion of 50mug. of histamine dihydrochloride. In 10 of these subjects the fall in V.C. and F.E.V.(1) produced by intravenous histamine is inhibited by the(More)
PURPOSE To determine the minimum detectable difference (MDD) and investigate variability of region-of-interest (ROI) analysis of apparent diffusion coefficient (ADC) and fractional anisotropy (FA) in acute ischemic stroke. MATERIALS AND METHODS Ten patients with acute stroke (<24 hours) and moderate-to-large infarcts were imaged using a fast diffusion(More)
Two groups of hospital inpatients, one with asthma and the other with chronic bronchitis were studied during the course of an acute episode. All had comparable airways obstruction and were free of cardiac involvement. They were treated on roughly similar lines and without the use of adrenal corticosteroids or any other agent that may influence body water(More)
  • M Govindaraj
  • The Indian journal of chest diseases & allied…
  • 1991
The effect of corticosteroid drugs on sputum production was studied in 74 patients of asthma. They were alternatively allotted to two different treatment schedules-conventional bronchodilator drugs alone and bronchodilators plus corticosteroids. All the subjects recovered, bringing out sputum in the process. However, the steroid treated group produced(More)
In this retrospective study, incidence of nevirapine (NVP) toxicity in children who were switched from efavirenz (EFV) to NVP (treatment experienced [TE] group) was compared with that of children who had started NVP-based antiretroviral therapy directly (treatment naïve [TN] group). This study also identified risk factors associated with development of NVP(More)
A group of 50 asthmatics and another of 27 subjects with emphysema were interviewed with regard to the nature of dyspnea. They were in particular asked whether their difficulty was during inspiration or in expiration. Asthmatics chiefly described dyspnea as inspiratory while the majority of the emphysema group were unable to relate their distress to either(More)