Miroslav Subotic

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OBJECTIVES Adaptations of the alveolar ridge after tooth loss have been well described. However, studies on the morphometric characteristics of cortical bone are rare; hence, this study of human atrophic edentulous mandibles was undertaken. MATERIAL AND METHODS Total cortical area, porosity, and thickness, and the percentage of cortical area in the(More)
Penicillin is known to cause allergic reactions with different clinical manifestations and possible immunologic mechanisms. The purpose of this study was to follow cases of established hypersensitivity to penicillin and its possible development into chronic urticaria. 35 patients with a clinical picture of acute urticaria and with or without angioedema were(More)
With regard to the existing possibility favored by many immunologists that study on neutrophil (N) and monocyte (Mo) may throw light on the pathogenetic mechanism of clinical conditions such as psoriasis, the effect of PUVA therapy on human N and Mo chemotaxis in psoriasis vulgaris (PV) was investigated. One hundred psoriatic patients with severe clinical(More)
In order to contribute to the setting of an accurate diagnosis and prophylaxis of phytodermatitis (PD) and to better understand eczematogenic characteristics of some plants, we present results of an allergologic analysis and review the plants which most commonly cause FD in our material. A total of 15 patients presenting with FD was examined. In all the(More)
The authors present results of examining phagocytotic activity of polymorphonuclear (PMN) granulocytes in patients with psoriasis vulgaris from the aspect of applied PUVA-therapy. 100 patients with psoriasis vulgaris were examined and divided into three groups, 20 patients with acute exanthematous form of the disease, 16 patients with chronic stationary(More)
INTRODUCTION Former investigations of Koebner phenomenon had demonstrated its higher incidence in patients with severe generalized and/or unstable forms of psoriasis which expressed increased resistance to various treatment modalities. The aim of this study was to establish the correlation between the presence of Koebner phenomenon and the PUVA therapy(More)
In dermatology Isotretinoin has been used for 16 years in cases of serious clinical forms of acne resistant to common therapy. This paper presents actual knowledge on pharmacokinetics of isotretinoin, mechanisms of its action, side effects, the newest clinical indications for its application in acne therapy and other possible indications in the contemporary(More)
INTRODUCTION Koebner phenomenon in psoriasis presents development of psoriatic lesions, after injury of uninvolved skin, which are identical in morphology with the previous trauma. The aim of this study was to establish the correlation of Koebner phenomenon with sex and age distribution, clinical variants of psoriasis vulgaris, age of onset and incidence in(More)
INTRODUCTION Erythema dyschromicum perstans (ashy dermatosis) is a very rare skin disease included in the group of acquired, idiopathic hypermelanosis, with development of blue-gray macules. This disease appears more frequently in dark coloured persons, especially women in the first and second life decade. CASE REPORT A male patient, 42 years of age, was(More)
In consideration of confirmed disturbances of some functional activities of neutrophils and monocytes in patients with psoriasis vulgaris, this work had a purpose to investigate chaemotactic activity of neutrophils and monocytes in patients with psoriasis vulgaris. Totaly were examined 100 patients with psoriasis vulgaris, which were devidede in three(More)